| Literature DB >> 12505259 |
Yi Kong Keung1, Michael Beaty, William Steward, Bethy Jackle, Mark Pettnati.
Abstract
Chronic myelocytic leukemia (CML) is a chronic myeloproliferative disorder characterized by cytogenetic or molecular evidence of Philadelphia (Ph) chromosome, t(9;22)(q34;q11). Mild to moderate eosinophilia is commonly seen in CML. However, eosinophilia as a dominant feature of CML is extremely rare. We describe a case of Ph(-) CML with eosinophilia. Loeffler endocarditis, and t(9;12)(q34;p13) that resulted in an ETV6-ABL gene rearrangement/fusion identified to the best of our knowledge, for the first time by using commercially available fluorescence in situ hybridization probes.Entities:
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Year: 2002 PMID： 12505259 DOI： 10.1016/s0165-4608(02)00609-x
Source DB: PubMed Journal: Cancer Genet Cytogenet ISSN： 0165-4608