BACKGROUND: Length of stay (LOS) after surgery is a major determinant of resource utilization for colorectal cancer (CRC). The purpose of this study was to examine the association between pretreatment health-related quality of life (HRQL) scores and postoperative hospital LOS in a cohort of patients undergoing surgery for CRC. METHODS: Seventy patients with biopsy-proven CRC were enrolled in an IRB-approved, prospective study. Information was collected concerning standard perioperative variables. Prior to surgery, all patients also completed the CRC-specific module of the Functional Assessment of Cancer Therapy (FACT-C). Perioperative variables and FACT-C scores were compared with LOS in both univariate and multivariate analysis. LOS for those patients scoring in the lowest quartile on FACT-C was compared with LOS for patients scoring in the remaining quartiles. RESULTS: Median length of stay for the entire group was 6 (range 3-25) days. In univariate analysis, surgical complications (10.6 vs 6.6 days; P = 0.001) and with poorer FACT-C individual scale scores for Physical Well-Being (9.1 vs 7.3 days; P = 0.04), Functional Well-Being (9.6 vs 7.1 days; P = 0.006), and Colorectal Cancer Concerns (9.5 vs 7.1 days; P = 0.01) were all significantly associated with increased length of stay. In multivariate analysis, surgical morbidity (OR = 5.6; 95% CI 1.5-21.4), age >72 (OR = 6.0; 95% CI 1.6-23.5), and low FACT-C total score (OR = 4.2; 95% CI 1.1-15.6) were independently associated with increased LOS. CONCLUSIONS: Pretreatment HRQL scores as measured by FACT-C may be of benefit in the prediction of LOS. Such information may be an important and currently neglected means of risk-adjusting populations undergoing surgery for colorectal cancer for this outcome.
BACKGROUND: Length of stay (LOS) after surgery is a major determinant of resource utilization for colorectal cancer (CRC). The purpose of this study was to examine the association between pretreatment health-related quality of life (HRQL) scores and postoperative hospital LOS in a cohort of patients undergoing surgery for CRC. METHODS: Seventy patients with biopsy-proven CRC were enrolled in an IRB-approved, prospective study. Information was collected concerning standard perioperative variables. Prior to surgery, all patients also completed the CRC-specific module of the Functional Assessment of Cancer Therapy (FACT-C). Perioperative variables and FACT-C scores were compared with LOS in both univariate and multivariate analysis. LOS for those patients scoring in the lowest quartile on FACT-C was compared with LOS for patients scoring in the remaining quartiles. RESULTS: Median length of stay for the entire group was 6 (range 3-25) days. In univariate analysis, surgical complications (10.6 vs 6.6 days; P = 0.001) and with poorer FACT-C individual scale scores for Physical Well-Being (9.1 vs 7.3 days; P = 0.04), Functional Well-Being (9.6 vs 7.1 days; P = 0.006), and Colorectal Cancer Concerns (9.5 vs 7.1 days; P = 0.01) were all significantly associated with increased length of stay. In multivariate analysis, surgical morbidity (OR = 5.6; 95% CI 1.5-21.4), age >72 (OR = 6.0; 95% CI 1.6-23.5), and low FACT-C total score (OR = 4.2; 95% CI 1.1-15.6) were independently associated with increased LOS. CONCLUSIONS: Pretreatment HRQL scores as measured by FACT-C may be of benefit in the prediction of LOS. Such information may be an important and currently neglected means of risk-adjusting populations undergoing surgery for colorectal cancer for this outcome.
Authors: Ryan D Nipp; Carolyn L Qian; Helen P Knight; Cristina R Ferrone; Hiroko Kunitake; Carlos Fernandez-Del Castillo; Michael Lanuti; Motaz Qadan; Rocco Ricciardi; Keith D Lillemoe; Brandon Temel; Ardeshir Z Hashmi; Erin Scott; Erin Stevens; Grant R Williams; Zhi Ven Fong; Terrence A O'Malley; Esteban Franco-Garcia; Nora K Horick; Vicki A Jackson; Joseph A Greer; Areej El-Jawahri; Jennifer S Temel Journal: J Geriatr Oncol Date: 2022-01-21 Impact factor: 3.929
Authors: Jorunn Drageset; Reidun Karin Sandvik; Leslie Sofia Pareja Eide; Gunhild Austrheim; Mary Fox; Elisabeth Grov Beisland Journal: Health Qual Life Outcomes Date: 2021-03-20 Impact factor: 3.186
Authors: Maren Schmidt; Rahel Eckardt; Kathrin Scholtz; Bruno Neuner; Vera von Dossow-Hanfstingl; Jalid Sehouli; Christian G Stief; Klaus-Dieter Wernecke; Claudia D Spies Journal: PLoS One Date: 2015-09-17 Impact factor: 3.240
Authors: Kathleen J Yost; Elizabeth A Hahn; Alan M Zaslavsky; John Z Ayanian; Dee W West Journal: Health Qual Life Outcomes Date: 2008-08-25 Impact factor: 3.186