Literature DB >> 12504790

Beneficial effect of pharmacological mobilization of bone marrow in experimental cerebral ischemia.

Isabelle Six1, Gaëlle Gasan, Emmanuelle Mura, Régis Bordet.   

Abstract

Bone marrow stem cells are able to differentiate into nervous and endothelial cells. In our study, we found that administration of a bone marrow-stimulating factor (granulocyte colony-stimulating factor; G-CSF 50 microg/kg) decrease the brain infarct volume and enhance survival rate in a model of cerebral ischemia. Taken together, these data suggest a beneficial effect of a pharmacological endogenous bone marrow mobilization in the course of cerebral ischemia and open a new direction for cellular therapy strategy in stroke.

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Year:  2003        PMID： 12504790     DOI： 10.1016/s0014-2999(02)02785-1

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  33 in total

Review 1.  Stem cell therapy for cerebral ischemia: from basic science to clinical applications.

Authors:  Koji Abe; Toru Yamashita; Shunya Takizawa; Satoshi Kuroda; Hiroyuki Kinouchi; Nobutaka Kawahara
Journal:  J Cereb Blood Flow Metab       Date:  2012-01-18       Impact factor: 6.200

2.  The hematopoietic factor G-CSF is a neuronal ligand that counteracts programmed cell death and drives neurogenesis.

Authors:  Armin Schneider; Carola Krüger; Tobias Steigleder; Daniela Weber; Claudia Pitzer; Rico Laage; Jaroslaw Aronowski; Martin H Maurer; Nikolaus Gassler; Walter Mier; Martin Hasselblatt; Rainer Kollmar; Stefan Schwab; Clemens Sommer; Alfred Bach; Hans-Georg Kuhn; Wolf-Rüdiger Schäbitz
Journal:  J Clin Invest       Date:  2005-07-07       Impact factor: 14.808

Review 3.  Neuroprotection through G-CSF: recent advances and future viewpoints.

Authors:  Vikrant Rahi; Sumit Jamwal; Puneet Kumar
Journal:  Pharmacol Rep       Date:  2021-01-02       Impact factor: 3.024

4.  Time-dependent effect of combination therapy with erythropoietin and granulocyte colony-stimulating factor in a mouse model of hypoxic-ischemic brain injury.

Authors:  Ji Hea Yu; Jung Hwa Seo; Jong Eun Lee; Ji Hoe Heo; Sung-Rae Cho
Journal:  Neurosci Bull       Date:  2014-01-16       Impact factor: 5.203

Review 5.  Hematopoietic stem cells are pluripotent and not just "hematopoietic".

Authors:  Makio Ogawa; Amanda C LaRue; Meenal Mehrotra
Journal:  Blood Cells Mol Dis       Date:  2013-02-27       Impact factor: 3.039

6.  G-CSF, rt-PA and combination therapy after experimental thromboembolic stroke.

Authors:  Rainer Kollmar; Nils Henninger; Christian Urbanek; Stefan Schwab
Journal:  Exp Transl Stroke Med       Date:  2010-04-14

7.  Granulocyte-colony stimulating factor for stroke treatment: mechanisms of action and efficacy in preclinical studies.

Authors:  Jens Minnerup; Sevgi Sevimli; Wolf-Rüdiger Schäbitz
Journal:  Exp Transl Stroke Med       Date:  2009-10-21

8.  Turning Death to Growth: Hematopoietic Growth Factors Promote Neurite Outgrowth through MEK/ERK/p53 Pathway.

Authors:  Mei Gao; Li-Ru Zhao
Journal:  Mol Neurobiol       Date:  2017-11-08       Impact factor: 5.590

9.  Granulocyte colony-stimulating factor (G-CSF) protects oligodendrocyte and promotes hindlimb functional recovery after spinal cord injury in rats.

Authors:  Ryo Kadota; Masao Koda; Junko Kawabe; Masayuki Hashimoto; Yutaka Nishio; Chikato Mannoji; Tomohiro Miyashita; Takeo Furuya; Akihiko Okawa; Kazuhisa Takahashi; Masashi Yamazaki
Journal:  PLoS One       Date:  2012-11-27       Impact factor: 3.240

10.  Administration of recombinant human granulocyte colony-stimulating factor (rhG-CSF) for the intracranial hemorrhage in two dogs: a case report.

Authors:  M H Kang; H M Park
Journal:  Iran J Vet Res       Date:  2016       Impact factor: 1.376
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