PURPOSE: To report a case of acute multifocal placoid pigment epitheliopathy (AMPPE)-like lesion as an early presentation of subacute sclerosing panencephalitis (SSPE). DESIGN: Observational case report. METHODS: A 21-year-old woman presented with a profound loss of vision in the left eye. The initial clinical picture was characterized by a whitish infiltration of the macular area and papillary edema in the left eye. Six days later multiple chorioretinal infiltrations were present in the peripheral fundus of the left eye, which led to the diagnosis of AMPPE. RESULTS: During the following year, a gradual change in her personality developed. The diagnosis of SSPE was made by cerebrospinal fluid examination. Her clinical condition deteriorated rapidly, and she died. CONCLUSIONS: AMPPE can be accompanied by central nervous system involvement. We wish to emphasize the importance of considering the diagnosis of SSPE in cases of AMPPE.
PURPOSE: To report a case of acute multifocal placoid pigment epitheliopathy (AMPPE)-like lesion as an early presentation of subacute sclerosing panencephalitis (SSPE). DESIGN: Observational case report. METHODS: A 21-year-old woman presented with a profound loss of vision in the left eye. The initial clinical picture was characterized by a whitish infiltration of the macular area and papillary edema in the left eye. Six days later multiple chorioretinal infiltrations were present in the peripheral fundus of the left eye, which led to the diagnosis of AMPPE. RESULTS: During the following year, a gradual change in her personality developed. The diagnosis of SSPE was made by cerebrospinal fluid examination. Her clinical condition deteriorated rapidly, and she died. CONCLUSIONS: AMPPE can be accompanied by central nervous system involvement. We wish to emphasize the importance of considering the diagnosis of SSPE in cases of AMPPE.