Literature DB >> 12504682

Structure and function of the Arp2/3 complex.

Thomas D Pollard1, Christopher C Beltzner.   

Abstract

The Arp2/3 complex, a 220 kDa macromolecular assembly comprising two actin-related proteins and five other subunits, plays a key role in cellular motility by initiating the polymerization of new actin filaments. Crystal and cryo-electron microscopic structures of the Arp2/3 complex and branch junctions have clarified extensive biochemical data on the mechanism of this process.

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Year:  2002        PMID: 12504682     DOI: 10.1016/s0959-440x(02)00396-2

Source DB:  PubMed          Journal:  Curr Opin Struct Biol        ISSN: 0959-440X            Impact factor:   6.809


  40 in total

1.  Two deafness-causing (DFNA20/26) actin mutations affect Arp2/3-dependent actin regulation.

Authors:  Karina A Kruth; Peter A Rubenstein
Journal:  J Biol Chem       Date:  2012-06-20       Impact factor: 5.157

Review 2.  Deconstructing signal transduction pathways that regulate the actin cytoskeleton in dendritic spines.

Authors:  Peter Penzes; Michael E Cahill
Journal:  Cytoskeleton (Hoboken)       Date:  2012-03-12

3.  Two important polymers cross paths.

Authors:  James A Spudich
Journal:  Proc Natl Acad Sci U S A       Date:  2004-11-02       Impact factor: 11.205

Review 4.  New insights into cytoskeletal remodeling during platelet production.

Authors:  Dorsaf Ghalloussi; Ankita Dhenge; Wolfgang Bergmeier
Journal:  J Thromb Haemost       Date:  2019-07-16       Impact factor: 5.824

Review 5.  The function of actin-binding proteins in pollen tube growth.

Authors:  Haiyun Ren; Yun Xiang
Journal:  Protoplasma       Date:  2007-04-24       Impact factor: 3.356

6.  Molecular dynamics simulation and coarse-grained analysis of the Arp2/3 complex.

Authors:  Jim Pfaendtner; Gregory A Voth
Journal:  Biophys J       Date:  2008-09-19       Impact factor: 4.033

7.  Automated tracing of filaments in 3D electron tomography reconstructions using Sculptor and Situs.

Authors:  Mirabela Rusu; Zbigniew Starosolski; Manuel Wahle; Alexander Rigort; Willy Wriggers
Journal:  J Struct Biol       Date:  2012-03-13       Impact factor: 2.867

8.  Actin filament bundling by fimbrin is important for endocytosis, cytokinesis, and polarization in fission yeast.

Authors:  Colleen T Skau; David S Courson; Andrew J Bestul; Jonathan D Winkelman; Ronald S Rock; Vladimir Sirotkin; David R Kovar
Journal:  J Biol Chem       Date:  2011-06-03       Impact factor: 5.157

9.  Actin-like protein 1 (ALP1) is a component of dynamic, high molecular weight complexes in Toxoplasma gondii.

Authors:  Jennifer L Gordon; Jeffrey S Buguliskis; Paul J Buske; L David Sibley
Journal:  Cytoskeleton (Hoboken)       Date:  2010-01

Review 10.  The WASP and WAVE family proteins.

Authors:  Shusaku Kurisu; Tadaomi Takenawa
Journal:  Genome Biol       Date:  2009-06-15       Impact factor: 13.583

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