| Literature DB >> 12504682 |
Thomas D Pollard1, Christopher C Beltzner.
Abstract
The Arp2/3 complex, a 220 kDa macromolecular assembly comprising two actin-related proteins and five other subunits, plays a key role in cellular motility by initiating the polymerization of new actin filaments. Crystal and cryo-electron microscopic structures of the Arp2/3 complex and branch junctions have clarified extensive biochemical data on the mechanism of this process.Entities:
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Year: 2002 PMID: 12504682 DOI: 10.1016/s0959-440x(02)00396-2
Source DB: PubMed Journal: Curr Opin Struct Biol ISSN: 0959-440X Impact factor: 6.809