Literature DB >> 12502883

Yellow fever virus replicons as an expression system for hepatitis C virus structural proteins.

Richard Molenkamp1, Engbert A Kooi, Marjoleine A Lucassen, Sophie Greve, Joyphi C P Thijssen, Willy J M Spaan, Peter J Bredenbeek.   

Abstract

Chimeric yellow fever virus (YF) RNAs were constructed in which the YF structural genes were replaced by the hepatitis C virus (HCV) structural genes or fusions between the YF and HCV structural genes. Interestingly, RNA replication required nucleotide complementarity between the 3'-located conserved sequence 1 and an RNA sequence located in the 5' end of the YF capsid sequence. The (chimeric-)HCV structural proteins were efficiently expressed and processed, and the native E1/E2 heterodimer was formed. However, no indication for the production of HCV-like particles was obtained.

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Year:  2003        PMID： 12502883      PMCID： PMC140782          DOI： 10.1128/jvi.77.2.1644-1648.2003

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  29 in total

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Authors:  Anne Op De Beeck; Laurence Cocquerel; Jean Dubuisson
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2.  Conserved elements in the 3' untranslated region of flavivirus RNAs and potential cyclization sequences.

Authors:  C S Hahn; Y S Hahn; C M Rice; E Lee; L Dalgarno; E G Strauss; J H Strauss
Journal:  J Mol Biol       Date:  1987-11-05       Impact factor: 5.469

3.  Hepatitis C virus-like particle morphogenesis.

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Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

4.  Cell-associated West Nile flavivirus is covered with E+pre-M protein heterodimers which are destroyed and reorganized by proteolytic cleavage during virus release.

Authors:  G Wengler; G Wengler
Journal:  J Virol       Date:  1989-06       Impact factor: 5.103

5.  Synthesis and secretion of recombinant tick-borne encephalitis virus protein E in soluble and particulate form.

Authors:  S L Allison; K Stadler; C W Mandl; C Kunz; F X Heinz
Journal:  J Virol       Date:  1995-09       Impact factor: 5.103

6.  Nucleotide sequence of yellow fever virus: implications for flavivirus gene expression and evolution.

Authors:  C M Rice; E M Lenches; S R Eddy; S J Shin; R L Sheets; J H Strauss
Journal:  Science       Date:  1985-08-23       Impact factor: 47.728

7.  Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells.

Authors:  Masanori Ikeda; MinKyung Yi; Kui Li; Stanley M Lemon
Journal:  J Virol       Date:  2002-03       Impact factor: 5.103

8.  Persistent and transient replication of full-length hepatitis C virus genomes in cell culture.

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Journal:  J Virol       Date:  2002-04       Impact factor: 5.103

9.  Formation and intracellular localization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia and Sindbis viruses.

Authors:  J Dubuisson; H H Hsu; R C Cheung; H B Greenberg; D G Russell; C M Rice
Journal:  J Virol       Date:  1994-10       Impact factor: 5.103

10.  Expression and identification of hepatitis C virus polyprotein cleavage products.

Authors:  A Grakoui; C Wychowski; C Lin; S M Feinstone; C M Rice
Journal:  J Virol       Date:  1993-03       Impact factor: 5.103
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  19 in total

1.  Incorporation of tick-borne encephalitis virus replicons into virus-like particles by a packaging cell line.

Authors:  Rainer Gehrke; Michael Ecker; Stephan W Aberle; Steven L Allison; Franz X Heinz; Christian W Mandl
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2.  Structure and function of the 3' terminal six nucleotides of the west nile virus genome in viral replication.

Authors:  Mark Tilgner; Pei-Yong Shi
Journal:  J Virol       Date:  2004-08       Impact factor: 5.103

3.  Functional analysis of the tick-borne encephalitis virus cyclization elements indicates major differences between mosquito-borne and tick-borne flaviviruses.

Authors:  Regina M Kofler; Verena M Hoenninger; Caroline Thurner; Christian W Mandl
Journal:  J Virol       Date:  2006-04       Impact factor: 5.103

4.  Temperature-dependent production of pseudoinfectious dengue reporter virus particles by complementation.

Authors:  Camilo Ansarah-Sobrinho; Steevenson Nelson; Christiane A Jost; Stephen S Whitehead; Theodore C Pierson
Journal:  Virology       Date:  2008-09-17       Impact factor: 3.616

5.  A mouse cell-adapted NS4B mutation attenuates West Nile virus RNA synthesis.

Authors:  Francesc Puig-Basagoiti; Mark Tilgner; Corey J Bennett; Yangsheng Zhou; Jorge L Muñoz-Jordán; Adolfo García-Sastre; Kristen A Bernard; Pei-Yong Shi
Journal:  Virology       Date:  2006-12-18       Impact factor: 3.616

6.  Control of translation by the 5'- and 3'-terminal regions of the dengue virus genome.

Authors:  Wei-Wei Chiu; Richard M Kinney; Theo W Dreher
Journal:  J Virol       Date:  2005-07       Impact factor: 5.103

7.  An RNA pseudoknot is required for production of yellow fever virus subgenomic RNA by the host nuclease XRN1.

Authors:  Patrícia A G C Silva; Carina F Pereira; Tim J Dalebout; Willy J M Spaan; Peter J Bredenbeek
Journal:  J Virol       Date:  2010-08-25       Impact factor: 5.103

8.  Tetracycline-inducible packaging cell line for production of flavivirus replicon particles.

Authors:  Tracey J Harvey; Wen Jun Liu; Xiang Ju Wang; Richard Linedale; Michael Jacobs; Andrew Davidson; Thuy T T Le; Itaru Anraku; Andreas Suhrbier; Pei-Yong Shi; Alexander A Khromykh
Journal:  J Virol       Date:  2004-01       Impact factor: 5.103

9.  Engineering the Japanese encephalitis virus RNA genome for the expression of foreign genes of various sizes: implications for packaging capacity and RNA replication efficiency.

Authors:  Sang-Im Yun; Yu-Jeong Choi; Xiao-Fang Yu; Jae-Young Song; Young-Hak Shin; Young-Ran Ju; Seok-Yong Kim; Young-Min Lee
Journal:  J Neurovirol       Date:  2007-12       Impact factor: 2.643

10.  Functional analysis of mosquito-borne flavivirus conserved sequence elements within 3' untranslated region of West Nile virus by use of a reporting replicon that differentiates between viral translation and RNA replication.

Authors:  Michael K Lo; Mark Tilgner; Kristen A Bernard; Pei-Yong Shi
Journal:  J Virol       Date:  2003-09       Impact factor: 5.103
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