Literature DB >> 12502332

New cytotoxic xenia diterpenoids from the Formosan soft coral Xenia umbellata.

Chang-Yih Duh1, Ali Ali H El-Gamal, Chin-Ying Chiang, Chih-Ju Chu, Shang-Kwei Wang, Chang-Feng Dai.   

Abstract

Seven new cytotoxic xenicane-type diterpenoids, 9-deoxyxeniloide-E (1), 9-deoxy-7,8-epoxyxeniloide-E (2), xeniolide-G (3), 9-deoxyxenialactol-C (4), xenibecin (5), xeniolide-H (6), and xenitacin (7), were isolated from the methylene chloride solubles of the Formosan soft coral Xenia umbellata. The structures were elucidated by 1D and 2D NMR spectral analysis, and their cytotoxicity against selected cancer cells was measured in vitro.

Entities:  

Mesh：

Substances：

Year:  2002        PMID： 12502332     DOI： 10.1021/np020268z

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  4 in total

1.  Induction of apoptosis by diterpenes from the soft coral Xenia elongata.

Authors:  Eric H Andrianasolo; Liti Haramaty; Kurt Degenhardt; Robin Mathew; Eileen White; Richard Lutz; Paul Falkowski
Journal:  J Nat Prod       Date:  2007-09-28       Impact factor: 4.050

2.  Mode of action of diterpene and characterization of related metabolites from the soft coral, Xenia elongata.

Authors:  Eric H Andrianasolo; Liti Haramaty; Eileen White; Richard Lutz; Paul Falkowski
Journal:  Mar Drugs       Date:  2014-02-20       Impact factor: 5.118

Review 3.  Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms.

Authors:  Tatjana Huber; Lara Weisheit; Thomas Magauer
Journal:  Beilstein J Org Chem       Date:  2015-12-10       Impact factor: 2.883

Review 4.  Terpenoids from Marine Soft Coral of the Genus Xenia in 1977 to 2019.

Authors:  Shean-Yeaw Ng; Chin-Soon Phan; Takahiro Ishii; Takashi Kamada; Toshiyuki Hamada; Charles Santhanaraju Vairappan
Journal:  Molecules       Date:  2020-11-18       Impact factor: 4.411
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.