Literature DB >> 12501487

[The Baikal scullcap (Scutellaria baicalensis Georgi)--a potential source of new drugs].

J Martin1, J Dusek.   

Abstract

The scullcap (Scutellaria baicalensis Georgi) is a medicinal plant of traditional Chinese medicine and the drug--Scutellariae radix--is, because of its antioxidant, antiviral, antibacterial, antiinflammatory, antiallergic, and sedative properties, the subject of intensive development. This paper reports the results of pharmacological-toxicological studies of this drug and its flavonids approximately from the year 1990 till the year 2001. The results confirm the validity of traditional use and at the same time indicate that some flavonoids have more utilizable therapeutic effects. Mainly baicalein seems to be a prospective medicine for the treatment of some kinds of cancer.

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Year:  2002        PMID: 12501487

Source DB:  PubMed          Journal:  Ceska Slov Farm        ISSN: 1210-7816


  5 in total

1.  Effects and Mechanism of Baicalin on Apoptosis of Cervical Cancer HeLa Cells I n -v itro.

Authors:  Yong Peng; Zhan-Zhao Fu; Cong-Shan Guo; Yan-Xia Zhang; Ya Di; Bin Jiang; Qing-Wang Li
Journal:  Iran J Pharm Res       Date:  2015       Impact factor: 1.696

2.  Baicalin increases developmental competence of mouse embryos in vitro by inhibiting cellular apoptosis and modulating HSP70 and DNMT expression.

Authors:  Xiaonan Qi; Huatao Li; Xia Cong; Xin Wang; Zhongling Jiang; Rongfeng Cao; Wenru Tian
Journal:  J Reprod Dev       Date:  2016-07-29       Impact factor: 2.214

3.  Baicalein inhibits pancreatic cancer cell proliferation and invasion via suppression of NEDD9 expression and its downstream Akt and ERK signaling pathways.

Authors:  Rong-Tao Zhou; Mei He; Ze Yu; Yang Liang; Yuzhe Nie; Sheng Tai; Chun-Bo Teng
Journal:  Oncotarget       Date:  2017-04-07

4.  Antifungal activity and mechanism of action of Ou-gon (Scutellaria root extract) components against pathogenic fungi.

Authors:  Xia Da; Yayoi Nishiyama; Duerna Tie; Kyaw Zaw Hein; Osamu Yamamoto; Eishin Morita
Journal:  Sci Rep       Date:  2019-02-08       Impact factor: 4.379

5.  Protective Effect of Scutellaria litwinowii Extract on Serum/Glucose-Deprived Cultured PC12 Cells and Determining the Role of Reactive Oxygen Species.

Authors:  Maryam Afsharzadeh; Zahra Tayarani-Najaran; Aryo Zare; Seyed Hadi Mousavi
Journal:  J Toxicol       Date:  2012-07-19
  5 in total

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