Literature DB >> 12500630

[Operated and unoperated coarctation of the aorta in the adult].

L Auriacombe1.   

Abstract

The common denominator of patients operated for isthmic coarctation of the aorta in childhood who reach adulthood, is the risk of hypertension which is observed in about 70% of cases with its cortege of cerebral and coronary vascular complications or left ventricular hypertrophy, which considerably reduce life expectancy. Systematic follow-up of these patients includes, in addition to clinical and echocardiographic examination, three essential investigations: exercise stress testing, the study of arterial mechanics and angio MRI. Hypertension on exercise is observed in 70% of patients of whom 21% have critical hypertension despite excellent anatomical correction. Vascular study shows changes in arterial eactivity and endothelial function independent of the age at operation: MRI often demonstrates aortic irregularities which partially explain the hypertension. Three therapeutic choices are available: in cases of restenosis, balloon angioplasty with or without stenting gives good results: when hypoplasia of the aorta is observed, a surgical repair is recommended: otherwise, pharmacological treatment with life style adaptation including carefully managed physical exercise is appropriate. Coarctation diagnosed in adulthood is rare but poses special problems. Treatment by angioplasty is possible but is complicated by aneurysms of the isthmus in 20% of cases so that nowadays surgery is the treatment of choice. This is difficult and dangerous because of the collateral circulation, the fragility of the aorta and the risk of medullary ischaemia. Resection-anastomosis is the most effective technique with or without cardiopulmonary bypass, reducing the hypertension in 70% of cases.

Entities:  

Mesh:

Year:  2002        PMID: 12500630

Source DB:  PubMed          Journal:  Arch Mal Coeur Vaiss        ISSN: 0003-9683


  3 in total

1.  An unusual case of multiple aortic abnormalities: total occlusion of aortic arch, left external iliac artery, and bicuspid aortic valve in a 21-year-old man.

Authors:  Asli Tanindi; Yusuf Tavil; Ruya Mutluay; Hacer Taktak; Atiye Cengel
Journal:  Heart Vessels       Date:  2007-03-23       Impact factor: 2.037

2.  Endovascular treatment of late thoracic aortic aneurysms after surgical repair of congenital aortic coarctation in childhood.

Authors:  Robert Juszkat; Bartlomiej Perek; Bartosz Zabicki; Olga Trojnarska; Marek Jemielity; Ryszard Staniszewski; Wiesław Smoczyk; Fryderyk Pukacki
Journal:  PLoS One       Date:  2013-12-26       Impact factor: 3.240

3.  Familial aortic coarctation: a rare cause of refractory hypertension in the elderly: a case report.

Authors:  Carmen M Lara-Rojas; M Rosa Bernal-Lopez; M Dolores Lopez-Carmona; Ricardo Gomez-Huelgas
Journal:  Medicine (Baltimore)       Date:  2015-01       Impact factor: 1.889

  3 in total

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