Literature DB >> 12499233

Molecular characterization of quinolone-resistant Neisseria gonorrhoeae in Hong Kong.

Kai Man Kam1, Shirley Sin Yee Kam, Danny Tze Leung Cheung, Viola Wai Na Tung, Wai Fun Au, May May Cheung.   

Abstract

In Hong Kong, ParC changes among high-level quinolone-resistant Neisseria gonorrhoeae (QRNG) isolates at Ser-87-->Arg were associated with a higher level of resistance than a Ser-87-->Ile alteration. Two previously undescribed mutations in clinical isolates occurring in gyrA, conferring Ala-92-->Pro and Asp-95-->Tyr changes, were detected. Nine different outer membrane lipoprotein (Lip) repeat classes-11 to 19 repeats-were identified, with repeat lengths of 16 and 17 the most common, indicating considerable strain diversity.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12499233      PMCID： PMC148972          DOI： 10.1128/AAC.47.1.436-439.2003

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  12 in total

1.  Identification of novel mutation patterns in the parC gene of ciprofloxacin-resistant isolates of Neisseria gonorrhoeae.

Authors:  D L Trees; A L Sandul; W L Whittington; J S Knapp
Journal:  Antimicrob Agents Chemother       Date:  1998-08       Impact factor: 5.191

2.  Molecular epidemiology of Neisseria gonorrhoeae exhibiting decreased susceptibility and resistance to ciprofloxacin in Hawaii, 1991-1999.

Authors:  D L Trees; A L Sandul; S W Neal; H Higa; J S Knapp
Journal:  Sex Transm Dis       Date:  2001-06       Impact factor: 2.830

3.  Alterations within the quinolone resistance-determining regions of GyrA and ParC of Neisseria gonorrhoeae isolated in the Far East and the United States.

Authors:  D L Trees; A L Sandul; V Peto-Mesola; M R Aplasca; H B Leng; W L Whittington; J S Knapp
Journal:  Int J Antimicrob Agents       Date:  1999-08       Impact factor: 5.283

4.  Use of the neisserial lipoprotein (Lip) for subtyping Neisseria gonorrhoeae.

Authors:  D L Trees; A J Schultz; J S Knapp
Journal:  J Clin Microbiol       Date:  2000-08       Impact factor: 5.948

5.  Correlation of in vitro susceptibilities to newer quinolones of naturally occurring quinolone-resistant Neisseria gonorrhoeae strains with changes in GyrA and ParC.

Authors:  T R Shultz; J W Tapsall; P A White
Journal:  Antimicrob Agents Chemother       Date:  2001-03       Impact factor: 5.191

6.  Molecular basis of high-level ciprofloxacin resistance in Neisseria gonorrhoeae strains isolated in Denmark from 1995 to 1998.

Authors:  X Su; I Lind
Journal:  Antimicrob Agents Chemother       Date:  2001-01       Impact factor: 5.191

7.  Susceptibilities of Neisseria gonorrhoeae isolates containing amino acid substitutions in GyrA, with or without substitutions in ParC, to newer fluoroquinolones and other antibiotics.

Authors:  M Tanaka; H Nakayama; M Haraoka; T Saika; I Kobayashi; S Naito
Journal:  Antimicrob Agents Chemother       Date:  2000-01       Impact factor: 5.191

8.  Quinolone-resistant Neisseria gonorrhoeae in Hong Kong.

Authors:  K M Kam; P W Wong; M M Cheung; N K Ho; K K Lo
Journal:  Sex Transm Dis       Date:  1996 Mar-Apr       Impact factor: 2.830

9.  Analysis of quinolone resistance mechanisms in Neisseria gonorrhoeae isolates in vitro.

Authors:  M Tanaka; S Sakuma; K Takahashi; T Nagahuzi; T Saika; I Kobayashi; J Kumazawa
Journal:  Sex Transm Infect       Date:  1998-02       Impact factor: 3.519

10.  Rapid decline in penicillinase-producing Neisseria gonorrhoeae in Hong Kong associated with emerging 4-fluoroquinolone resistance.

Authors:  K M Kam; K K Lo; N K Ho; M M Cheung
Journal:  Genitourin Med       Date:  1995-06
View more
  4 in total

1.  Persistence Dynamics of Antimicrobial-Resistant Neisseria in the Pharynx of Rhesus Macaques.

Authors:  Eliza Thapa; Hanna M Knauss; Benjamin A Colvin; Benjamin A Fischer; Nathan J Weyand
Journal:  Antimicrob Agents Chemother       Date:  2020-07-22       Impact factor: 5.191

2.  Molecular characterization of quinolone-resistant Neisseria gonorrhoeae isolates from Brazil.

Authors:  Aline A Uehara; Efigênia L T Amorin; Maria de Fátima Ferreira; Claudia F Andrade; Maysa B M Clementino; Ivano de Filippis; Felipe P G Neves; Tatiana de C A Pinto; Lúcia M Teixeira; Marcia Giambiagi-Demarval; Sérgio E L Fracalanzza
Journal:  J Clin Microbiol       Date:  2011-10-05       Impact factor: 5.948

3.  Detection of gyrA and parC mutations associated with ciprofloxacin resistance in Neisseria gonorrhoeae by use of oligonucleotide biochip technology.

Authors:  Wenming Zhou; Weidong Du; Huimin Cao; Jianlong Zhao; Sen Yang; Wei Li; Yujun Shen; Shumei Zhang; Wenhui Du; Xuejun Zhang
Journal:  J Clin Microbiol       Date:  2004-12       Impact factor: 5.948

4.  Fluoroquinolone resistance and mutation patterns in gyrA and parC genes in Neisseria gonorrhoeae isolates from Shanghai, China.

Authors:  Tiejun Zhang; Xiaoming Zhou; Yue Chen; Weiming Gu; Tao Zhang; Qingwu Jiang
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2009-02-18
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.