| Literature DB >> 12499075 |
Shrabana Chakrabarti1, Tuhin Kanti Biswas, Begum Rokeya, Liaquat Ali, M Mosihuzzaman, Nilufer Nahar, A K Azad Khan, Biswapati Mukherjee.
Abstract
Caesalpinia bonducella, widely distributed throughout the coastal region of India and used ethnically by the tribal people of India for controlling blood sugar was earlier reported by us to possess hypoglycemic activity in animal model. This prompted us to undertake a detail study with the aqueous and ethanolic extracts of the seeds of this plant in both type 1 and 2 diabetes mellitus in Long Evans rats. Significant blood sugar lowering effect (P < 0.05) of C. bonducella was observed in type 2 diabetic model. Special emphasis was given on the mechanistic study by gut absorption of glucose and liver glycogen. Copyright 2002 Elsevier Science Ireland Ltd.Entities:
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Year: 2003 PMID： 12499075 DOI： 10.1016/s0378-8741(02)00262-3
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360