| Literature DB >> 12498878 |
Abstract
The glycosyltransferases GtfE and GtfD from the vancomycin producer Amycolatopsis orientalis have promiscuous substrate and NDP-sugar specificities. They have been used to generate novel glycopeptide antibiotics containing the heptapeptide scaffolds of vancomycin and teichoplanin.Entities:
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Year: 2002 PMID: 12498878 DOI: 10.1016/s1074-5521(02)00289-2
Source DB: PubMed Journal: Chem Biol ISSN: 1074-5521