Literature DB >> 12497316

[Impairment, disability and handicap scales in multiple sclerosis].

T Arbizu-Urdiain1, A Martínez-Yélamos, V Casado Ruiz.   

Abstract

INTRODUCTION AND
METHOD: In recent years the need to create scales for measuring the dysfunction or impairment suffered by patients with multiple sclerosis has increased. The aim of the scales that measure neurological impairment is two fold: to homogenise the data from different series so that studies into the prognosis and natural history of the disease can be compared, and to measure the changes in the progress of the disease when a therapy has been established. Over the past few years a large number of scales have appeared that attempt to redress the shortcomings of the EDSS (Expanded Disability Status Scale). The latest of these, the MSF Composite, manages to overcome the statistical problems of the EDSS and enables significant differences between two groups to be detected when studying the effect of a treatment.
CONCLUSIONS: In the coming years we will possibly witness a joint use of several of the scales described, and both the EDSS and the Composite will be employed together in the evaluation of patients in therapeutic protocols, perhaps together with a quality of life scale.

Entities:  

Mesh:

Year:  2002        PMID: 12497316

Source DB:  PubMed          Journal:  Rev Neurol        ISSN: 0210-0010            Impact factor:   0.870


  1 in total

1.  A novel approach to estimate the minimally important difference for the Fatigue Impact Scale in multiple sclerosis patients.

Authors:  Regina Rendas-Baum; Min Yang; Francoise Cattelin; Gene V Wallenstein; John D Fisk
Journal:  Qual Life Res       Date:  2010-07-10       Impact factor: 4.147

  1 in total

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