Literature DB >> 12497071

High risk genes predisposing to prostate cancer development-do they exist?

R Singh1, R A Eeles, F Durocher, J Simard, S Edwards, M Badzioch, Z Kote-Jarai, D Teare, D Ford, D Dearnaley, A Ardern-Jones, A Murkin, A Dowe, R Shearer, J Kelly, F Labrie, D Easton, S A Narod, P N Tonin, W D Foulkes.   

Abstract

There is evidence for genetic predisposition to prostate cancer. However, prostate cancer genes have been more difficult to find than genes for some of the other common cancers, such as breast and colon cancer. The reasons for this are discussed in this article and it is now becoming clear that prostate cancer is probably due to multiple genes, many of which are moderate or low penetrance. The advances in the Human Genome Project and technology, especially that of robotics, will help to overcome these problems. Prostate Cancer and Prostatic Diseases (2000) 3, 241-247

Entities:  

Year:  2000        PMID: 12497071     DOI: 10.1038/sj.pcan.4500478

Source DB:  PubMed          Journal:  Prostate Cancer Prostatic Dis        ISSN: 1365-7852            Impact factor:   5.554


  5 in total

1.  Identification of a prostate cancer susceptibility locus on chromosome 7q11-21 in Jewish families.

Authors:  Danielle M Friedrichsen; Janet L Stanford; Sarah D Isaacs; Marta Janer; Bao-Li Chang; Kerry Deutsch; Elizabeth Gillanders; Suzanne Kolb; Katherine E Wiley; Michael D Badzioch; S Lilly Zheng; Patrick C Walsh; Gail P Jarvik; Leroy Hood; Jeffrey M Trent; William B Isaacs; Elaine A Ostrander; Jianfeng Xu
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-09       Impact factor: 11.205

Review 2.  Prostate cancer susceptibility loci: finding the genes.

Authors:  Elanie A Ostrander; Bo Johannesson
Journal:  Adv Exp Med Biol       Date:  2008       Impact factor: 2.622

3.  No association between polymorphism in the vascular endothelial growth factor gene at position -460 and sporadic prostate cancer in the Turkish population.

Authors:  Ilke H Onen; Ece Konac; Muzaffer Eroglu; Cagri Guneri; Hasan Biri; Abdullah Ekmekci
Journal:  Mol Biol Rep       Date:  2007-01-11       Impact factor: 2.316

4.  Investigation of Chromosome 1 Aberrations in the Lymphocytes of Prostate Cancer and Benign Prostatic Hyperplasia Patients by Fluorescence in situ Hybridization.

Authors:  Justyna Miszczyk; Mikołaj Przydacz; Michał Zembrzuski; Piotr L Chłosta
Journal:  Cancer Manag Res       Date:  2021-05-31       Impact factor: 3.989

5.  The clinical genetics of prostate cancer.

Authors:  Sashi Kommu; Stephen Edwards; Rosalind Eeles
Journal:  Hered Cancer Clin Pract       Date:  2004-07-15       Impact factor: 2.857

  5 in total

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