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Literature DB >> 12496213

Induction of emetic response to staphylococcal enterotoxins in the house musk shrew (Suncus murinus).

Dong-Liang Hu¹, Katsuhiko Omoe, Yu Shimoda, Akio Nakane, Kunihiro Shinagawa.

Abstract

The emetic responses induced by staphylococcal enterotoxin A (SEA), SEB, SEC2, SED, SEE, SEG, SEH, and SEI in the house musk shrew (Suncus murinus) were investigated. SEA, SEE, and SEI showed higher emetic activity in the house musk shrew than the other SEs. SEB, SEC2, SED, SEG, and SEH also induced emetic responses in this animal model but relatively high doses were required. The house musk shrew appears to be a valuable model for studying the mechanisms of emetic reactions caused by SEs.

Entities: Chemical Species

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Year: 2003 PMID： 12496213 PMCID： PMC143409 DOI： 10.1128/IAI.71.1.567-570.2003

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

28 in total

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7. Identification and characterization of a new staphylococcal enterotoxin-related putative toxin encoded by two kinds of plasmids.

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