Literature DB >> 12496212

Feasibility of an HA2 domain-based periodontitis vaccine.

A A DeCarlo1, Y Huang, C A Collyer, D B Langley, J Katz.   

Abstract

In a rat periodontitis model, preinoculation with the Porphyromonas gingivalis HA2 binding domain for hemoglobin provided protection from disease. Protection was associated with induced anti-HA2 immunoglobulin G (IgG) humoral antibodies. The IgG subclass ratios suggested that relatively lower Th2/Th1-driven responses were directly associated with protection when rHA2 was administered in saline.

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Year:  2003        PMID： 12496212      PMCID： PMC143394          DOI： 10.1128/IAI.71.1.562-566.2003

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  35 in total

1.  Cytokine profiles of T-lymphocytes from gingival tissues with pathological pocketing.

Authors:  O Takeichi; J Haber; T Kawai; D J Smith; I Moro; M A Taubman
Journal:  J Dent Res       Date:  2000-08       Impact factor: 6.116

2.  Periodontal disease and risk of cerebrovascular disease: the first national health and nutrition examination survey and its follow-up study.

Authors:  T Wu; M Trevisan; R J Genco; J P Dorn; K L Falkner; C T Sempos
Journal:  Arch Intern Med       Date:  2000-10-09

3.  Association between extent of periodontal attachment loss and self-reported history of heart attack: an analysis of NHANES III data.

Authors:  S J Arbes; G D Slade; J D Beck
Journal:  J Dent Res       Date:  1999-12       Impact factor: 6.116

4.  Effect of lipopolysaccharide from Porphyromonas gingivalis on prostaglandin E2 and interleukin-1-beta release from rat periosteal and human gingival fibroblasts in vitro.

Authors:  H J Sismey-Durrant; R M Hopps
Journal:  Oral Microbiol Immunol       Date:  1991-12

Review 5.  Impact of oral diseases on systemic health in the elderly: diabetes mellitus and aspiration pneumonia.

Authors:  G W Taylor; W J Loesche; M S Terpenning
Journal:  J Public Health Dent       Date:  2000       Impact factor: 1.821

Review 6.  Microbiology of periodontal disease.

Authors:  W E Moore
Journal:  J Periodontal Res       Date:  1987-09       Impact factor: 4.419

7.  Extraoral control of geometry for digital subtraction radiography.

Authors:  M K Jeffcoat; M S Reddy; R L Webber; R C Williams; U E Ruttimann
Journal:  J Periodontal Res       Date:  1987-09       Impact factor: 4.419

8.  Potential associations between chronic respiratory disease and periodontal disease: analysis of National Health and Nutrition Examination Survey III.

Authors:  F A Scannapieco; A W Ho
Journal:  J Periodontol       Date:  2001-01       Impact factor: 6.993

9.  Binding specificity of the Porphyromonas gingivalis heme and hemoglobin receptor HmuR, gingipain K, and gingipain R1 for heme, porphyrins, and metalloporphyrins.

Authors:  T Olczak; D W Dixon; C A Genco
Journal:  J Bacteriol       Date:  2001-10       Impact factor: 3.490

Review 10.  Destructive periodontitis lesions are determined by the nature of the lymphocytic response.

Authors:  E Gemmell; K Yamazaki; G J Seymour
Journal:  Crit Rev Oral Biol Med       Date:  2002
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  5 in total

Review 1.  Toll gates to periodontal host modulation and vaccine therapy.

Authors:  George Hajishengallis
Journal:  Periodontol 2000       Date:  2009       Impact factor: 7.589

2.  Role of Porphyromonas gingivalis phosphoserine phosphatase enzyme SerB in inflammation, immune response, and induction of alveolar bone resorption in rats.

Authors:  Brian Bainbridge; Raj K Verma; Christie Eastman; Bilal Yehia; Mercedes Rivera; Catherine Moffatt; Indraneel Bhattacharyya; Richard J Lamont; Lakshmyya Kesavalu
Journal:  Infect Immun       Date:  2010-08-30       Impact factor: 3.441

3.  Humoral responses to Porphyromonas gingivalis gingipain adhesin domains in subjects with chronic periodontitis.

Authors:  Ky-Anh Nguyen; Arthur A DeCarlo; Mayuri Paramaesvaran; Charles A Collyer; David B Langley; Neil Hunter
Journal:  Infect Immun       Date:  2004-03       Impact factor: 3.441

4.  Porphyromonas gingivalis and Treponema denticola Mixed Microbial Infection in a Rat Model of Periodontal Disease.

Authors:  Raj K Verma; Sunethra Rajapakse; Archana Meka; Clayton Hamrick; Sheela Pola; Indraneel Bhattacharyya; Madhu Nair; Shannon M Wallet; Ikramuddin Aukhil; Lakshmyya Kesavalu
Journal:  Interdiscip Perspect Infect Dis       Date:  2010-05-31

5.  Immunization with cell-free-generated vaccine protects from Porphyromonas gingivalis-induced alveolar bone loss.

Authors:  Nasi Huang; Elyse Shimomura; Gang Yin; Cuong Tran; Aaron Sato; Alex Steiner; Tyler Heibeck; Michelle Tam; Jeffery Fairman; Frank C Gibson
Journal:  J Clin Periodontol       Date:  2019-01-31       Impact factor: 8.728
  5 in total

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