Literature DB >> 12496206

Vibrio vulnificus induces macrophage apoptosis in vitro and in vivo.

Takashige Kashimoto1, Shunji Ueno, Miyuki Hanajima, Hisae Hayashi, Yukihiro Akeda, Shinichi Miyoshi, Toshiharu Hongo, Takeshi Honda, Nobuyuki Susa.   

Abstract

In this study, we compared the apoptotic activities of clinical and environmental isolates of Vibrio vulnificus toward macrophages in vitro and in vivo. The clinical isolates induced apoptosis in macrophage-like cells in vitro and in macrophages in vivo. This suggests that macrophage apoptosis may be important for the clinical virulence of V. vulnificus.

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Year:  2003        PMID: 12496206      PMCID: PMC143416          DOI: 10.1128/IAI.71.1.533-535.2003

Source DB:  PubMed          Journal:  Infect Immun        ISSN: 0019-9567            Impact factor:   3.441


  22 in total

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Review 2.  Pathogen-induced apoptosis of macrophages: a common end for different pathogenic strategies.

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  16 in total

1.  VvpM, an extracellular metalloprotease of Vibrio vulnificus, induces apoptotic death of human cells.

Authors:  Mi-Ae Lee; Jeong-A Kim; Yu Jin Yang; Mee-Young Shin; Soon-Jung Park; Kyu-Ho Lee
Journal:  J Microbiol       Date:  2014-11-03       Impact factor: 3.422

2.  Monoclonal antibodies against Vibrio vulnificus RtxA1 elicit protective immunity through distinct mechanisms.

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Review 3.  Whipple's disease: a macrophage disease.

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5.  Chitin-induced carbotype conversion in Vibrio vulnificus.

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6.  Dynamic expressions of liver tissue apoptosis-related genes of Vibrio vulnificus sepsis rats and the effects of antibacterial agents.

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7.  Vibrio vulnificus damages macrophages during the early phase of infection.

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Journal:  Infect Immun       Date:  2007-06-25       Impact factor: 3.441

8.  MukB Is a Gene Necessary for Rapid Proliferation of Vibrio vulnificus in the Systemic Circulation but Not at the Local Infection Site in the Mouse Wound Infection Model.

Authors:  Takashige Kashimoto; Kohei Yamazaki; Takehiro Kado; Kaho Matsuda; Shunji Ueno
Journal:  Microorganisms       Date:  2021-04-27

Review 9.  The regulator HlyU, the repeat-in-toxin gene rtxA1, and their roles in the pathogenesis of Vibrio vulnificus infections.

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10.  The Makes Caterpillars Floppy (MCF)-Like Domain of Vibrio vulnificus Induces Mitochondrion-Mediated Apoptosis.

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