Literature DB >> 12495032

A 3D doubly sensitivity enhanced X-filtered TOCSY-TOCSY experiment.

Hugo van Ingen1, Marco Tessari, Geerten W Vuister.   

Abstract

We present a 3D double sensitivity enhanced X-filtered homonuclear TOCSY-TOCSY experiment for the assignment of unlabeled molecules complexed to labeled protein- or nucleic acid-domains. The resulting spectrum is clean, can be measured in a reasonable amount of time and allows for increased resolution of overlapping resonances when compared to 2D methods. The 3D X-filtered TOCSY-TOCSY allows for assignment in cases where the size or the composition of the unlabeled molecule results in a high degree of overlap.

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Year:  2002        PMID： 12495032     DOI： 10.1023/a:1020975705237

Source DB:  PubMed          Journal:  J Biomol NMR        ISSN： 0925-2738            Impact factor:   2.835


  21 in total

Review 1.  Mapping protein-protein interactions in solution by NMR spectroscopy.

Authors:  Erik R P Zuiderweg
Journal:  Biochemistry       Date:  2002-01-08       Impact factor: 3.162

2.  Sequence-specific assignment of the PAH2 domain of Sin3B free and bound to Mad1.

Authors:  C A Spronk; J F Jansen; M Tessari; A M Kaan; J Aelen; E Lasonder; H G Stunnenberg; G W Vuister
Journal:  J Biomol NMR       Date:  2001-04       Impact factor: 2.835

Review 3.  Structure-based screening and design in drug discovery.

Authors:  Maria van Dongen; Johan Weigelt; Jonas Uppenberg; Johan Schultz; Mats Wikström
Journal:  Drug Discov Today       Date:  2002-04-15       Impact factor: 7.851

4.  Doubly sensitivity-enhanced 3D TOCSY-HSQC.

Authors:  S S Wijmenga; C P van Mierlo; E Steensma
Journal:  J Biomol NMR       Date:  1996-10       Impact factor: 2.835

5.  The atomic structure of protein-protein recognition sites.

Authors:  L Lo Conte; C Chothia; J Janin
Journal:  J Mol Biol       Date:  1999-02-05       Impact factor: 5.469

6.  Assignment strategies in homonuclear three-dimensional 1H NMR spectra of proteins.

Authors:  G W Vuister; R Boelens; A Padilla; G J Kleywegt; R Kaptein
Journal:  Biochemistry       Date:  1990-02-20       Impact factor: 3.162

7.  Solution structure of a calmodulin-target peptide complex by multidimensional NMR.

Authors:  M Ikura; G M Clore; A M Gronenborn; G Zhu; C B Klee; A Bax
Journal:  Science       Date:  1992-05-01       Impact factor: 47.728

8.  NMRPipe: a multidimensional spectral processing system based on UNIX pipes.

Authors:  F Delaglio; S Grzesiek; G W Vuister; G Zhu; J Pfeifer; A Bax
Journal:  J Biomol NMR       Date:  1995-11       Impact factor: 2.835

Review 9.  Molecular mechanisms of calmodulin's functional versatility.

Authors:  M Zhang; T Yuan
Journal:  Biochem Cell Biol       Date:  1998       Impact factor: 3.626

10.  Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions.

Authors:  M Piotto; V Saudek; V Sklenár
Journal:  J Biomol NMR       Date:  1992-11       Impact factor: 2.835
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