| Literature DB >> 12493586 |
Thierry Le Bricon1, Djaouida Bengoufa, Mourad Benlakehal, Bernard Bousquet, Danielle Erlich.
Abstract
Evaluate the Freelite free light chain immunoassay for urine analysis in myeloma. Urine specimens from 20 patients were analyzed by Freelite (The Binding Site) and SDS-agarose gel electrophoresis (Hydragel protéinurie, Sebia). Using the kappa/lambda ratio, Freelite was more sensitive than electrophoresis to detect free light chains, but concentration was overestimated in 75% of cases. Despite high sensitivity and full automation, Freelite inaccurately measures monoclonal free light chains in urine.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12493586 DOI： 10.1016/s0009-9120(02)00386-7
Source DB: PubMed Journal: Clin Biochem ISSN： 0009-9120 Impact factor: 3.281