Literature DB >> 1249347

Hypersensitivity to procarbazine associated with angioedema, urticaria, and low serum complement activity.

M M Glovsky, J Braunwald, G Opelz, A Alenty.   

Abstract

Hypersensitivity to procarbazine associated with urticaria, angioedema, and painful joint swelling was found in a 20-year-old student being treated for Hodgkin's disease. A marked fall in complement component activity occurred simultaneously with the development of symtoms. It is suggested that generation of products of complement component activation could be important in the pathogenesis of hypersensitivity to some drugs.

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Year:  1976        PMID: 1249347     DOI: 10.1016/0091-6749(76)90032-4

Source DB:  PubMed          Journal:  J Allergy Clin Immunol        ISSN: 0091-6749            Impact factor:   10.793


  3 in total

Review 1.  Urticaria--current concepts.

Authors:  A Taaffe
Journal:  Postgrad Med J       Date:  1977-12       Impact factor: 2.401

Review 2.  Hypersensitivity reactions from antineoplastic agents.

Authors:  R B Weiss; J R Baker
Journal:  Cancer Metastasis Rev       Date:  1987       Impact factor: 9.264

3.  Procarbazine, lomustine and vincristine toxicity in low-grade gliomas.

Authors:  G Jutras; K Bélanger; N Letarte; J-P Adam; D Roberge; B Lemieux; É Lemieux-Blanchard; L Masucci; C Ménard; J P Bahary; R Moumdjian; F Berthelet; M Florescu
Journal:  Curr Oncol       Date:  2018-02-28       Impact factor: 3.677

  3 in total

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