Y Lecrubier1. 1. INSERM, Hôpital de la Salpêtrière, Paris, France. lecru@ext.jussieu.fr
Abstract
OBJECTIVE: To underscore the need to attain remission in the treatment of depression, taking into consideration the appropriate definitions of response and remission, as well as the impact of residual symptomatology. METHOD: A review of research pertaining to successful response and remission of depression following antidepressant intervention, as identified by a comprehensive MEDLINE search. RESULTS: Complete remission is both critical and attainable with appropriate antidepressant therapy. CONCLUSION: While adequate response to antidepressant medication is desired, the ultimate goal of therapy is remission, the achievement of an asymptomatic state characterized by complete functional recovery.
OBJECTIVE: To underscore the need to attain remission in the treatment of depression, taking into consideration the appropriate definitions of response and remission, as well as the impact of residual symptomatology. METHOD: A review of research pertaining to successful response and remission of depression following antidepressant intervention, as identified by a comprehensive MEDLINE search. RESULTS: Complete remission is both critical and attainable with appropriate antidepressant therapy. CONCLUSION: While adequate response to antidepressant medication is desired, the ultimate goal of therapy is remission, the achievement of an asymptomatic state characterized by complete functional recovery.
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