| Literature DB >> 12492357 |
Christophe Lucatelli1, Florian Viton, Yves Gimbert, Andrew E Greene.
Abstract
Protected (3R,4S)-N-Boc-3-hydroxy-4-methyl-4-phenylazetidin-2-one has been synthesized stereoselectively and used to esterify protected 10-desacetylbaccatin III to give, following removal of the protecting groups, novel C-3' methyl taxotere (docetaxel).Entities:
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Year: 2002 PMID： 12492357 DOI： 10.1021/jo026460n
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354