Literature DB >> 12492354

An epiisopicropodophyllin aza analogue via palladium-catalyzed pseudo-domino cyclization.

Giovanni Poli1, Giuliano Giambastiani.   

Abstract

A new aza analogue of epiisopicropodophyllin (the C-3 epimer of podophyllotoxin) has been synthesized exploiting two original strategic steps. Rings A/B and E are entered at an early stage via a cationic benzhydrylation process. A palladium-catalyzed pseudo-domino (Pd-PDOM) intramolecular process generates rings C/D in a single synthetic operation.

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Year:  2002        PMID： 12492354     DOI： 10.1021/jo026068+

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  7-p-Tolyl-10,11-dihydro-benzo[h]furo[3,4-b]quinolin-8(7H)-one.

Authors:  Chunling Shi
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2010-02-20

2.  7-Methyl-9-p-tolyl-4,9-dihydro-furo[3,4-b]quinolin-1(3H)-one.

Authors:  Chunling Shi; Min Ji
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2008-12-13

3.  Synthesis and Pharmacological Screening of Pyridopyrimidines as Effective Anti-Diarrheal Agents through the Suppression of Cyclic Nucleotide Accumulation.

Authors:  Tiago Zaminelli; Elisa Magli; Francesco Frecentese; Caroline H Lescano; Rafael Campos; Irene Saccone; Angela Corvino; Paola Di Vaio; Flavia Giordano; Paolo Luciano; Ferdinando Fiorino; Elisa Perissutti; Vincenzo Santagada; Beatrice Severino; Giuseppe Caliendo; Gilberto De Nucci
Journal:  ChemistryOpen       Date:  2019-04-08       Impact factor: 2.911

4.  Switchable selectivity in Pd-catalyzed [3 + 2] annulations of γ-oxy-2-cycloalkenones with 3-oxoglutarates: C-C/C-C vs C-C/O-C bond formation.

Authors:  Yang Liu; Julie Oble; Giovanni Poli
Journal:  Beilstein J Org Chem       Date:  2019-05-16       Impact factor: 2.883

5.  Systematic Modification of Zingerone Reveals Structural Requirements for Attraction of Jarvis's Fruit Fly.

Authors:  Benjamin L Hanssen; Soo Jean Park; Jane E Royer; Joanne F Jamie; Phillip W Taylor; Ian M Jamie
Journal:  Sci Rep       Date:  2019-12-18       Impact factor: 4.379

6.  One-pot synthesis and property study on thieno[3,2-b]furan compounds.

Authors:  Weimin Ma; Jiawei Huang; Chao Li; Yueren Jiang; Baolin Li; Ting Qi; Xiaozhang Zhu
Journal:  RSC Adv       Date:  2019-03-01       Impact factor: 4.036
  6 in total

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