| Literature DB >> 12492348 |
Abstract
The [1 + 2] cycloaddition reaction of 1-iodoalkynes with difluorocarbene, generated from the decomposition of FSO(2)CF(2)COOSiMe(3) in diglyme in the presence of 10 mol % NaF at 120 degrees C, gives 3,3-difluoro-1-iodocyclopropenes in good yields. These new iodides can be trifluoromethylated and functionalized via the Heck reaction. The unusual hydrolytic reactions of the iodides under acidic conditions was also investigated.Entities:
Year: 2002 PMID： 12492348 DOI： 10.1021/jo020431v
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354