Literature DB >> 12491408

Design of a protein surface antagonist based on alpha-helix mimicry: inhibition of gp41 assembly and viral fusion.

Justin T Ernst1, Olaf Kutzki, Asim K Debnath, Shibo Jiang, Hong Lu, Andrew D Hamilton.   

Abstract

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Year:  2002        PMID： 12491408     DOI： 10.1002/1521-3773(20020118)41:2<278::aid-anie278>3.0.co;2-a

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  44 in total

Review 1.  Protein recognition using synthetic surface-targeted agents.

Authors:  Rishi Jain; Justin T Ernst; Olaf Kutzki; Hyung Soon Park; Andrew D Hamilton
Journal:  Mol Divers       Date:  2004       Impact factor: 2.943

2.  Galmic, a nonpeptide galanin receptor agonist, affects behaviors in seizure, pain, and forced-swim tests.

Authors:  Tamas Bartfai; Xiaoying Lu; Hedieh Badie-Mahdavi; Alasdair M Barr; Andrey Mazarati; Xiao-Ying Hua; Tony Yaksh; Gebhard Haberhauer; Susana Conde Ceide; Laurent Trembleau; Laszlo Somogyi; Lenz Kröck; Julius Rebek
Journal:  Proc Natl Acad Sci U S A       Date:  2004-07-06       Impact factor: 11.205

3.  Targeting a binding pocket within the trimer-of-hairpins: small-molecule inhibition of viral fusion.

Authors:  Christopher Cianci; David R Langley; Douglas D Dischino; Yaxiong Sun; Kuo-Long Yu; Anne Stanley; Julia Roach; Zhufang Li; Richard Dalterio; Richard Colonno; Nicholas A Meanwell; Mark Krystal
Journal:  Proc Natl Acad Sci U S A       Date:  2004-10-06       Impact factor: 11.205

4.  Extending foldamer design beyond α-helix mimicry: α/β-peptide inhibitors of vascular endothelial growth factor signaling.

Authors:  Holly S Haase; Kimberly J Peterson-Kaufman; Sheeny K Lan Levengood; James W Checco; William L Murphy; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2012-05-01       Impact factor: 15.419

5.  Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance.

Authors:  Brett D Welch; J Nicholas Francis; Joseph S Redman; Suparna Paul; Matthew T Weinstock; Jacqueline D Reeves; Yolanda S Lie; Frank G Whitby; Debra M Eckert; Christopher P Hill; Michael J Root; Michael S Kay
Journal:  J Virol       Date:  2010-08-18       Impact factor: 5.103

6.  Development of small molecules designed to modulate protein-protein interactions.

Authors:  Ye Che; Bernard R Brooks; Garland R Marshall
Journal:  J Comput Aided Mol Des       Date:  2006-04-19       Impact factor: 3.686

Review 7.  Targeting protein-protein interactions by rational design: mimicry of protein surfaces.

Authors:  Steven Fletcher; Andrew D Hamilton
Journal:  J R Soc Interface       Date:  2006-04-22       Impact factor: 4.118

8.  A novel fluorescence intensity screening assay identifies new low-molecular-weight inhibitors of the gp41 coiled-coil domain of human immunodeficiency virus type 1.

Authors:  Lifeng Cai; Miriam Gochin
Journal:  Antimicrob Agents Chemother       Date:  2007-04-23       Impact factor: 5.191

9.  Potent D-peptide inhibitors of HIV-1 entry.

Authors:  Brett D Welch; Andrew P VanDemark; Annie Heroux; Christopher P Hill; Michael S Kay
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-17       Impact factor: 11.205

10.  Binding of a potent small-molecule inhibitor of six-helix bundle formation requires interactions with both heptad-repeats of the RSV fusion protein.

Authors:  Dirk Roymans; Hendrik L De Bondt; Eric Arnoult; Peggy Geluykens; Tom Gevers; Marcia Van Ginderen; Nick Verheyen; Hidong Kim; Rudy Willebrords; Jean-François Bonfanti; Wouter Bruinzeel; Maxwell D Cummings; Herman van Vlijmen; Koen Andries
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-04       Impact factor: 11.205
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