Literature DB >> 12489949

Steroidal ureas as enantioselective receptors for an N-acetyl alpha-amino carboxylate.

Laura Siracusa1, Fionn M Hurley, Stefan Dresen, Laurence J Lawless, M Nieves Pérez-Payán, Anthony P Davis.   

Abstract

[reaction: see text] Cholic acid has been elaborated into three regioisomeric bis-carbamoylureas, which have been investigated as enantioselective receptors for N-acetyl phenylalanine. L/D selectivities, peaking at 5:1, have been determined by a sensitive and rapid MS-based extraction method that should be generalizable to related systems.

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Year:  2002        PMID: 12489949     DOI: 10.1021/ol027009l

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

Review 1.  Chemical and metabolic transformations of selected bile acids.

Authors:  K Kuhajda; S Kevresan; J Kandrac; J P Fawcett; M Mikov
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2006 Jul-Sep       Impact factor: 2.441

Review 2.  Bile acid scaffolds in supramolecular chemistry: the interplay of design and synthesis.

Authors:  Anthony P Davis
Journal:  Molecules       Date:  2007-08-29       Impact factor: 4.411

  2 in total

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