Literature DB >> 12488945

[Chagasic cardiopathy in endemic area versus sporadically infected patients].

Rubén Storino1, Sergio Auger, Oscar Caravello, María Inés Urrutia, Mariana Sanmartino, Miguel Jörg.   

Abstract

The aim of the study was to compare the degree of cardiac compromise between two patient groups infected with Chagas' disease, A) those permanently residing in endemic areas and B) those sporadically exposed to the parasite and indirectly (non-vector) infected (transfusion, mother-to-child transmission, etc.). The results show that patients sporadically infected presented a lower prevalence of cardiopathy, and when they do present cardiopathy, there is a lower prevalence of dilation when compared to infected patients residing in endemic areas. Also, the role of the parasite, number of reinfections, immunopathogenic mechanisms, quality of life and occupation are considered in the study of disease progression in each patient.

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Mesh:

Year:  2002        PMID: 12488945     DOI: 10.1590/s0034-89102002000700016

Source DB:  PubMed          Journal:  Rev Saude Publica        ISSN: 0034-8910            Impact factor:   2.106


  4 in total

1.  Genotyping of Trypanosoma cruzi sublineage in human samples from a North-East Argentina area by hybridization with DNA probes and specific polymerase chain reaction (PCR).

Authors:  Cristina Diez; Virginia Lorenz; Silvia Ortiz; Verónica Gonzalez; Andrea Racca; Iván Bontempi; Silvia Manattini; Aldo Solari; Iván Marcipar
Journal:  Am J Trop Med Hyg       Date:  2010-01       Impact factor: 2.345

2.  Cardiac condition in young chagasic women.

Authors:  O Lassen; G Dotto; S Ojeda; A Garutti; P Bertolotto; S Tabares; R Gallerano; A Sembaj
Journal:  J Med Life       Date:  2013-06-25

3.  Epidemiological modeling of Trypanosoma cruzi: Low stercorarian transmission and failure of host adaptive immunity explain the frequency of mixed infections in humans.

Authors:  Nicolás Tomasini; Paula Gabriela Ragone; Sébastien Gourbière; Juan Pablo Aparicio; Patricio Diosque
Journal:  PLoS Comput Biol       Date:  2017-05-08       Impact factor: 4.475

4.  Chronic Chagas cardiomyopathy: a review of the main pathogenic mechanisms and the efficacy of aetiological treatment following the BENznidazole Evaluation for Interrupting Trypanosomiasis (BENEFIT) trial.

Authors:  Anis Rassi; José Antonio Marin; Anis Rassi
Journal:  Mem Inst Oswaldo Cruz       Date:  2017-02-16       Impact factor: 2.743

  4 in total

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