| Literature DB >> 1248861 |
W D Stühlinger, P J Verroust, L Morel-Maroger.
Abstract
Sera from patients with various types of glomerulonephritis (GN) as well as sera from rabbits with acute serum sickness were studied for the presence of circulating immune complexes (IC). The method used is based on the observation that IC inhibit the uptake of IgG aggregates by guinea-pig peritoneal macrophages. Inhibition significantly greater than with normal human sera was found with sera of patients with membranous GN, membranoproliferative GN, focal glomerular sclerosis, minimal change nephrotic syndrome, acute septicaemic glomerular diseases and systemic lupus erythematous. IC were also detected in rabbits with acute serum sickness during the period of immune elimination.Entities:
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Year: 1976 PMID: 1248861 PMCID: PMC1444964
Source DB: PubMed Journal: Immunology ISSN: 0019-2805 Impact factor: 7.397