BACKGROUND: The role of frozen section (FS) in thyroid disease is controversial. The goal of this study was to identify a cohort of patients who may or may not benefit from FS. METHODS: Two hundred thirty-one patients who underwent thyroidectomy were evaluated in regard to fine-needle aspiration (FNA), FS, and the extent of surgery. RESULTS: In all, 155 patients underwent FNA, 140 patients underwent FS, and 103 patients had both. A final diagnosis of malignancy was obtained in 47 of 231 patients. FNA had a sensitivity of 50% and a specificity of 99%, and FS had a sensitivity of 50% and a specificity of 100% for diagnosing malignancy. Accounting for the clinical findings and FNA results, FS results altered the extent of thyroidectomy in 1 of 103 patients. CONCLUSIONS: The increased costs for the operative time and the pathologists needed to obtain routine FS are not supported with any substantial benefit in patient outcome.
BACKGROUND: The role of frozen section (FS) in thyroid disease is controversial. The goal of this study was to identify a cohort of patients who may or may not benefit from FS. METHODS: Two hundred thirty-one patients who underwent thyroidectomy were evaluated in regard to fine-needle aspiration (FNA), FS, and the extent of surgery. RESULTS: In all, 155 patients underwent FNA, 140 patients underwent FS, and 103 patients had both. A final diagnosis of malignancy was obtained in 47 of 231 patients. FNA had a sensitivity of 50% and a specificity of 99%, and FS had a sensitivity of 50% and a specificity of 100% for diagnosing malignancy. Accounting for the clinical findings and FNA results, FS results altered the extent of thyroidectomy in 1 of 103 patients. CONCLUSIONS: The increased costs for the operative time and the pathologists needed to obtain routine FS are not supported with any substantial benefit in patient outcome.
Authors: Hee Jung Moon; Jin Young Kwak; Eun-Kyung Kim; Min Jung Kim; Cheong Soo Park; Woung Youn Chung; Eun Ju Son Journal: World J Surg Date: 2009-05 Impact factor: 3.352
Authors: R G Gheri; E Romoli; V Vezzosi; B Ragghianti; S Bianchi; S Pedercini; F Dainelli; R Panconesi Journal: J Endocrinol Invest Date: 2010-12-15 Impact factor: 4.256
Authors: Luis Mauricio Hurtado-López; Sara Arellano-Montaño; Evelyn Migdalia Torres-Acosta; Felipe Rafael Zaldivar-Ramirez; Reyna Margarita Duarte-Torres; Patricia Alonso-De-Ruiz; Iván Martínez-Duncker; Carlos Martínez-Duncker Journal: Eur J Nucl Med Mol Imaging Date: 2004-05-06 Impact factor: 9.236