Literature DB >> 12487024

Molecular cloning, mRNA expression and chromosomal localization of mouse angiotensin-converting enzyme-related carboxypeptidase (mACE2).

Takami Komatsu1, Yutaka Suzuki, Junichi Imai, Sumio Sugano, Munetomo Hida, Akira Tanigami, Sawako Muroi, Yoshitsugu Yamada, Kazuo Hanaoka.   

Abstract

We isolated two mouse cDNA clones which show significant similarities with human angiotensin-converting enzyme-related carboxypeptidase (ACE2). The cDNAs were 2746 and 1995 bp in length and seemed to arise from the same gene by alternative splicing. The longer cDNA encoded a 798-amino acid protein containing the sequence motif conserved among zinc metallopeptidases. Mouse ACE2 showed 83% identity with human ACE2. Northern blot analysis revealed that 2.8- and 2.0-kb transcripts were expressed mainly in the kidney and the lungs. The mouse ACE2 gene was mapped to chromosome X 70.5 cM.

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Year:  2002        PMID： 12487024     DOI： 10.1080/1042517021000021608

Source DB:  PubMed          Journal:  DNA Seq        ISSN： 1026-7913


  32 in total

1.  Advances in the renin angiotensin system focus on angiotensin-converting enzyme 2 and angiotensin-(1-7).

Authors:  Carlos M Ferrario; Sarfaraz Ahmad; Janae Joyner; Jasmina Varagic
Journal:  Adv Pharmacol       Date:  2010

2.  Severe acute respiratory syndrome coronavirus infection of golden Syrian hamsters.

Authors:  Anjeanette Roberts; Leatrice Vogel; Jeannette Guarner; Norman Hayes; Brian Murphy; Sherif Zaki; Kanta Subbarao
Journal:  J Virol       Date:  2005-01       Impact factor: 5.103

3.  CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus.

Authors:  Scott A Jeffers; Sonia M Tusell; Laura Gillim-Ross; Erin M Hemmila; Jenna E Achenbach; Gregory J Babcock; William D Thomas; Larissa B Thackray; Mark D Young; Robert J Mason; Donna M Ambrosino; David E Wentworth; James C Demartini; Kathryn V Holmes
Journal:  Proc Natl Acad Sci U S A       Date:  2004-10-20       Impact factor: 11.205

4.  Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2.

Authors:  Wenhui Li; Thomas C Greenough; Michael J Moore; Natalya Vasilieva; Mohan Somasundaran; John L Sullivan; Michael Farzan; Hyeryun Choe
Journal:  J Virol       Date:  2004-10       Impact factor: 5.103

5.  Characterization of the first non-insect invertebrate functional angiotensin-converting enzyme (ACE): leech TtACE resembles the N-domain of mammalian ACE.

Authors:  Guillaume Rivière; Annie Michaud; Laurence Deloffre; Franck Vandenbulcke; Angélique Levoye; Christophe Breton; Pierre Corvol; Michel Salzet; Didier Vieau
Journal:  Biochem J       Date:  2004-09-01       Impact factor: 3.857

6.  The transcription factor HNF1α induces expression of angiotensin-converting enzyme 2 (ACE2) in pancreatic islets from evolutionarily conserved promoter motifs.

Authors:  Kim Brint Pedersen; Kavaljit H Chhabra; Van K Nguyen; Huijing Xia; Eric Lazartigues
Journal:  Biochim Biophys Acta       Date:  2013-10-05

7.  Androgens, the kidney, and COVID-19: an opportunity for translational research.

Authors:  Licy L Yanes Cardozo; Samar Rezq; Jacob E Pruett; Damian G Romero
Journal:  Am J Physiol Renal Physiol       Date:  2021-01-19

8.  Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent.

Authors:  Jun Liu; Hong Ji; Wei Zheng; Xie Wu; Janet J Zhu; Arthur P Arnold; Kathryn Sandberg
Journal:  Biol Sex Differ       Date:  2010-11-05       Impact factor: 5.027

9.  Recombinant Expression and Characterization of Human and Murine ACE2: Species-Specific Activation of the Alternative Renin-Angiotensin-System.

Authors:  Marko Poglitsch; Oliver Domenig; Cornelia Schwager; Stefan Stranner; Bernhard Peball; Evelyne Janzek; Bettina Wagner; Helmut Jungwirth; Hans Loibner; Manfred Schuster
Journal:  Int J Hypertens       Date:  2012-02-28       Impact factor: 2.420

10.  A crucial role in fertility for the oyster angiotensin-converting enzyme orthologue CgACE.

Authors:  Guillaume Riviere; Alexandre Fellous; Alban Franco; Benoit Bernay; Pascal Favrel
Journal:  PLoS One       Date:  2011-12-09       Impact factor: 3.240
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