Literature DB >> 12486490

Homocysteine and risk of open-angle glaucoma.

S Bleich1, A Jünemann, N von Ahsen, B Lausen, K Ritter, G Beck, G O H Naumann, J Kornhuber.   

Abstract

Homocysteine levels and the frequency of heterozygous methylenetetrahydrofolate reductase (MTHFR) C677T mutation are increased in open-angle glaucoma. Since homocysteine can induce vascular injury, alterations in extracellular matrix remodelling, and neuronal cell death, these findings may have important implications for understanding glaucomatous optic neuropathy.

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Year:  2002        PMID： 12486490     DOI： 10.1007/s007020200097

Source DB:  PubMed          Journal:  J Neural Transm (Vienna)        ISSN： 0300-9564            Impact factor:   3.575


  36 in total

1.  Sensitivity of staurosporine-induced differentiated RGC-5 cells to homocysteine.

Authors:  Preethi S Ganapathy; Ying Dun; Yonju Ha; Jennifer Duplantier; John Bradley Allen; Amina Farooq; B Renee Bozard; Sylvia B Smith
Journal:  Curr Eye Res       Date:  2010-01       Impact factor: 2.424

Review 2.  [PEX syndrome. Clinical diagnosis and systemic manifestations].

Authors:  E Scharfenberg; U Schlötzer-Schrehardt
Journal:  Ophthalmologe       Date:  2012-10       Impact factor: 1.059

3.  Homocysteine levels in aqueous humor and plasma of patients with primary open-angle glaucoma.

Authors:  J B Roedl; S Bleich; U Reulbach; N von Ahsen; U Schlötzer-Schrehardt; R Rejdak; G O H Naumann; F E Kruse; J Kornhuber; A G M Jünemann
Journal:  J Neural Transm (Vienna)       Date:  2006-08-24       Impact factor: 3.575

4.  Retinal Ganglion Cell Loss and Mild Vasculopathy in Methylene Tetrahydrofolate Reductase (Mthfr)-Deficient Mice: A Model of Mild Hyperhomocysteinemia.

Authors:  Shanu Markand; Alan Saul; Penny Roon; Puttur Prasad; Pamela Martin; Rima Rozen; Vadivel Ganapathy; Sylvia B Smith
Journal:  Invest Ophthalmol Vis Sci       Date:  2015-04       Impact factor: 4.799

5.  Molecular and biochemical characterization of folate transport proteins in retinal Müller cells.

Authors:  B Renee Bozard; Preethi S Ganapathy; Jennifer Duplantier; Barbara Mysona; Yonju Ha; Penny Roon; Robert Smith; I David Goldman; Puttur Prasad; Pamela M Martin; Vadivel Ganapathy; Sylvia B Smith
Journal:  Invest Ophthalmol Vis Sci       Date:  2010-01-06       Impact factor: 4.799

6.  Levels of circulating homocysteine, vitamin B6, vitamin B12, and folate in different types of open-angle glaucoma.

Authors:  Burak Turgut; Murat Kaya; Sermal Arslan; Tamer Demir; Mete Güler; Mehmet Kaan Kaya
Journal:  Clin Interv Aging       Date:  2010-04-26       Impact factor: 4.458

7.  Diabetes Accelerates Retinal Neuronal Cell Death In A Mouse Model of Endogenous Hyperhomocysteinemia.

Authors:  Preethi S Ganapathy; Penny Roon; Tracy K V E Moister; Barbara Mysona; Sylvia B Smith
Journal:  Ophthalmol Eye Dis       Date:  2009

8.  Endogenous elevation of homocysteine induces retinal neuron death in the cystathionine-beta-synthase mutant mouse.

Authors:  Preethi S Ganapathy; Brent Moister; Penny Roon; Barbara A Mysona; Jennifer Duplantier; Ying Dun; Tracy K V E Moister; Marlena J Farley; Puttur D Prasad; Kebin Liu; Sylvia B Smith
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-04-08       Impact factor: 4.799

9.  Association of MTHFR C677T polymorphism with primary open angle glaucoma: a Meta-analysis based on 18 case-control studies.

Authors:  Yu-Mei Yang; Yu-Ping Liu; Dong-Yu Li; Man Yu; Bo Gong; Lin Wang; Ping Shuai
Journal:  Int J Ophthalmol       Date:  2021-06-18       Impact factor: 1.779

10.  MTHFR gene C677T and A1298C polymorphisms and homocysteine levels in primary open angle and primary closed angle glaucoma.

Authors:  Shazia Micheal; Raheel Qamar; Farah Akhtar; Muhammad Imran Khan; Wajid Ali Khan; Asifa Ahmed
Journal:  Mol Vis       Date:  2009-11-09       Impact factor: 2.367
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