Literature DB >> 12485876

Dynamic localization/association of protein kinase CK2 subunits in living cells: a role in its cellular regulation?

Véronique Martel1, Odile Filhol, Arsenio Nueda, Claude Cochet.   

Abstract

Accumulating evidence indicates that in addition to the classical complex, the catalytic and regulatory subunits of CK2 can also exist as free populations in living cells. The association of recombinant CK2 subunits in vitro has been characterized, providing evidence for the first time for their targeted interactions in living cells. The data also suggest that the regulation by phosphorylation of many CK2 substrates may strongly depend on the dynamic localization/association of its subunits.

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Year:  2002        PMID： 12485876     DOI： 10.1111/j.1749-6632.2002.tb04648.x

Source DB:  PubMed          Journal:  Ann N Y Acad Sci        ISSN： 0077-8923            Impact factor:   5.691


  18 in total

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2.  Protein kinase CK2: a new view of an old molecular complex.

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4.  CK2 interacting proteins: emerging paradigms for CK2 regulation?

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5.  The interaction of CK2alpha and CK2beta, the subunits of protein kinase CK2, requires CK2beta in a preformed conformation and is enthalpically driven.

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Journal:  Protein Sci       Date:  2008-09-29       Impact factor: 6.725

Review 6.  Protein kinase CK2--a key suppressor of apoptosis.

Authors:  Kashif A Ahmad; Guixia Wang; Gretchen Unger; Joel Slaton; Khalil Ahmed
Journal:  Adv Enzyme Regul       Date:  2008-04-30

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8.  Structure-based design of small peptide inhibitors of protein kinase CK2 subunit interaction.

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9.  Phosphorylation of maize eukaryotic translation initiation factor 5A (eIF5A) by casein kinase 2: identification of phosphorylated residue and influence on intracellular localization of eIF5A.

Authors:  Maja Łebska; Arkadiusz Ciesielski; Lidia Szymona; Luiza Godecka; Elzbieta Lewandowska-Gnatowska; Jadwiga Szczegielniak; Grazyna Muszynska
Journal:  J Biol Chem       Date:  2009-12-15       Impact factor: 5.157

10.  Mass Spectrometry Reveals Protein Kinase CK2 High-Order Oligomerization via the Circular and Linear Assembly.

Authors:  Wei-Guang Seetoh; Daniel Shiu-Hin Chan; Dijana Matak-Vinković; Chris Abell
Journal:  ACS Chem Biol       Date:  2016-03-29       Impact factor: 5.100
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