| Literature DB >> 12485841 |
H-G Bernstein1, A Heinemann, D Krell, C Mawrin, H Bielau, P Danos, S Diekmann, G Keilhoff, B Bogerts, B Baumann.
Abstract
The cellular expression of nitric oxide synthase (NOS) was studied in neurons of the Nuc. suprachiasmaticus (SCN) of depressed patients and matched controls. The number of NOS-immunoreactive SCN neurons was significantly reduced in depression. We conclude that affective disorders are accompanied by impaired hypothalamic NO signaling.Entities:
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Year: 2002 PMID： 12485841 DOI： 10.1111/j.1749-6632.2002.tb04613.x
Source DB: PubMed Journal: Ann N Y Acad Sci ISSN： 0077-8923 Impact factor: 5.691