Literature DB >> 12484575

Duration of symptoms and spread of colorectal cancer: a short history does not mean early disease.

P R Kiran1, R E Glass.   

Abstract

The 5-year survival rates for colorectal cancer are generally lower in the UK than other European countries. In an attempt to improve prognosis, central government has stipulated that patients with suspicious symptoms ought to be seen within 2 weeks of referral from a primary care physician. In order to evaluate whether symptom duration affects stage at presentation of colorectal cancer, a retrospective analysis of all patients presenting over a 2-year period to a large district general hospital was performed. There was no significant difference (P = 0.885) in Dukes' staging in patients with symptoms lasting less or more than 6 months. Though seeing patients with symptoms suspicious of colorectal cancer in specialist out-patient clinics within 2 weeks of presentation to the primary care physician would probably reduce the number of patients presenting as an emergency, it is unlikely to improve prognosis. Thus funds diverted towards the 2-week wait are probably best utilised for other procedures such as colonoscopy and for improving care once the diagnosis of cancer has been made. Diagnosis of colorectal cancer at an earlier stage is best achieved by screening of the population.

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Year:  2002        PMID: 12484575      PMCID: PMC2504185          DOI: 10.1308/003588402760978157

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.891


  9 in total

1.  Urgent GP referrals for suspected lung, colorectal, prostate and ovarian cancer.

Authors:  Victoria L Allgar; Richard D Neal; Nasreen Ali; Brenda Leese; Phil Heywood; Gill Proctor; Joyce Evans
Journal:  Br J Gen Pract       Date:  2006-05       Impact factor: 5.386

Review 2.  Hematochezia in the young patient: a review of health-seeking behavior, physician attitudes, and controversies in management.

Authors:  Rashid Khan; David Hyman
Journal:  Dig Dis Sci       Date:  2009-02-24       Impact factor: 3.199

3.  Can early diagnosis of symptomatic colorectal cancer improve the prognosis?

Authors:  Fernando Gonzalez-Hermoso; Julian Perez-Palma; Joaquin Marchena-Gomez; Nieves Lorenzo-Rocha; Vincente Medina-Arana
Journal:  World J Surg       Date:  2004-06-16       Impact factor: 3.352

4.  Can we rely on a general practitioner's referral letter to a skin lesion clinic to prioritize appointments and does it make a difference to the patient's prognosis?

Authors:  Jill B Webb; A Khanna
Journal:  Ann R Coll Surg Engl       Date:  2006-01       Impact factor: 1.891

5.  Symptomatic presentation of early colorectal cancer.

Authors:  D Smith; M Ballal; R Hodder; G Soin; S N Selvachandran; D Cade
Journal:  Ann R Coll Surg Engl       Date:  2006-03       Impact factor: 1.891

6.  Delays in the diagnosis of six cancers: analysis of data from the National Survey of NHS Patients: Cancer.

Authors:  V L Allgar; R D Neal
Journal:  Br J Cancer       Date:  2005-06-06       Impact factor: 7.640

7.  The mortality of colorectal cancer in relation to the initial symptom at presentation to primary care and to the duration of symptoms: a cohort study using medical records.

Authors:  S Stapley; T J Peters; D Sharp; W Hamilton
Journal:  Br J Cancer       Date:  2006-10-24       Impact factor: 7.640

8.  Do diagnostic delays in cancer matter?

Authors:  R D Neal
Journal:  Br J Cancer       Date:  2009-12-03       Impact factor: 7.640

9.  Factors associated with consultation behaviour for primary symptoms potentially indicating colorectal cancer: a cross-sectional study on response to symptoms.

Authors:  Ryan J Courtney; Christine L Paul; Robert W Sanson-Fisher; Finlay A Macrae; John Attia; Mark McEvoy
Journal:  BMC Gastroenterol       Date:  2012-08-03       Impact factor: 3.067

  9 in total

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