Erling Ekerhovd1, Göran Westlander. 1. Center for Reproductive Medicine, Sahlgrenska University Hospital, Göteborg, Sweden. erling.ekerhovd@obgyn.gu.se
Abstract
PURPOSE: Klinefelter syndrome is the most common chromosomal aberration among azoospermic men. We wanted to compare testicular echogenicity and intratesticular arterial blood in men with this syndrome versus men with normal sperm parameters. METHODS: Testicular sonography including Doppler imaging, was performed as part of the infertility workup in 26 men with Klinefelter syndrome as well as in 26 men with normal sperm parameters. RESULTS: In men with Klinefelter syndrome, sonography of the testicular parenchyma revealed a heterogeneous irregular pattern with spread hyper- and hypoechoic foci. Doppler sonography resulted in waveforms of high impedance patterns, reflecting intratesticular blood flow of a high resistance. In men with normal sperm parameters testicular echogenicity was of an almost homogeneous regular pattern. In these men, intratesticular blood flow typically exhibited a pattern of low vascular resistance. CONCLUSIONS: The study demonstrates that testicular echogenicity as well as intratesticular blood flow are different in men with Klinefelter syndrome versus men with normal sperm parameters.
PURPOSE:Klinefelter syndrome is the most common chromosomal aberration among azoospermic men. We wanted to compare testicular echogenicity and intratesticular arterial blood in men with this syndrome versus men with normal sperm parameters. METHODS: Testicular sonography including Doppler imaging, was performed as part of the infertility workup in 26 men with Klinefelter syndrome as well as in 26 men with normal sperm parameters. RESULTS: In men with Klinefelter syndrome, sonography of the testicular parenchyma revealed a heterogeneous irregular pattern with spread hyper- and hypoechoic foci. Doppler sonography resulted in waveforms of high impedance patterns, reflecting intratesticular blood flow of a high resistance. In men with normal sperm parameters testicular echogenicity was of an almost homogeneous regular pattern. In these men, intratesticular blood flow typically exhibited a pattern of low vascular resistance. CONCLUSIONS: The study demonstrates that testicular echogenicity as well as intratesticular blood flow are different in men with Klinefelter syndrome versus men with normal sperm parameters.
Authors: A J Swerdlow; C Hermon; P A Jacobs; E Alberman; V Beral; M Daker; A Fordyce; S Youings Journal: Ann Hum Genet Date: 2001-03 Impact factor: 1.670
Authors: Laurence Rocher; Parvati Ramchandani; Jane Belfield; Michele Bertolotto; Lorenzo E Derchi; Jean Michel Correas; Raymond Oyen; Athina C Tsili; Ahmet Tuncay Turgut; Vikram Dogra; Karim Fizazi; Simon Freeman; Jonathan Richenberg Journal: Eur Radiol Date: 2015-10-24 Impact factor: 5.315