| Literature DB >> 12482430 |
Hyun Suk Lim1, Yong Seok Oh, Pann Ghill Suh, Sung Kee Chung.
Abstract
Sphingosine-1-phosphate (S1P) is considered to be an important regulator of diverse biological processes acting as a natural ligand to EDG receptors. As a preliminary study to develop potent and selective agonist and antagonist for EDG receptors, we report synthesis of S1P stereoisomers and analogues and their binding affinities to EDG-1, -3, and -5.Entities:
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Year: 2003 PMID： 12482430 DOI： 10.1016/s0960-894x(02)00893-4
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823