Literature DB >> 12481644

[Skin layer thickness at the ear of the domesticated pig , with special reference to the use of the ear integument for human dermatological research].

Wilfried Meyer1, Nils Holger Zschemisch.   

Abstract

Based on a shrinkage-free methodical approach (special plastic resin embedding, frozen section technique) and histological routine staining, the thickness of the different skin layers was measured from 15 regions of the outer and the inner side of the porcine auricle. Mean thickness values were for the str. corneum: 19 microns outside/20 microns inside, vital epidermis without ridges: 52 microns outside/56 microns inside, dermis: 1175 microns outside/1112 microns inside, hypodermis: 1024 microns outside/741 microns inside, perichondrium: 295 microns outside/220 microns inside. When both sides of the auricle were compared, it became obvious that the outer side generally had a thicker dermis (1140-1290 microns) and hypodermis (780-1150 microns), whereas the inner side had a thicker vital epidermis (50-60 microns) and deeper epidermal ridges (145-165 microns). The results are discussed with regard to corresponding findings from the human skin, and one region of the outer side of the porcine auricle is recommended as suitable for human dermatological research.

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Mesh:

Year:  2002        PMID: 12481644

Source DB:  PubMed          Journal:  Berl Munch Tierarztl Wochenschr        ISSN: 0005-9366            Impact factor:   0.328


  2 in total

1.  Evaluation of octyl p-methoxycinnamate included in liposomes and cyclodextrins in anti-solar preparations: preparations, characterizations and in vitro penetration studies.

Authors:  Mariana Sato de Souza de Bustamante Monteiro; Rafael Antonio Ozzetti; André Luiz Vergnanini; Lycia de Brito-Gitirana; Nadia Maria Volpato; Zaida Maria Faria de Freitas; Eduardo Ricci-Júnior; Elisabete Pereira dos Santos
Journal:  Int J Nanomedicine       Date:  2012-06-20

2.  In vitro delivery of novel, highly potent anti-varicella zoster virus nucleoside analogues to their target site in the skin.

Authors:  Chris A Jarvis; Chris McGuigan; Charles M Heard
Journal:  Pharm Res       Date:  2004-06       Impact factor: 4.580

  2 in total

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