Literature DB >> 12480170

Fluvoxamine suppresses the long-term potentiation in the hippocampal CA1 field of anesthetized rats: an effect mediated via 5-HT1A receptors.

Taku Kojima1, Machiko Matsumoto, Hiroko Togashi, Kaori Tachibana, Osamu Kemmotsu, Mitsuhiro Yoshioka.   

Abstract

A selective 5-HT reuptake inhibitor, fluvoxamine (10 and 30 mg/kg, i.p.) suppressed long-term potentiation (LTP) in the hippocampal CA1 field of anesthetized rats. Fluvoxamine (30 mg/kg, i.p.)-induced suppression of LTP was completely reversed by the 5-HT(1A) receptor antagonist NAN-190 (0.5 mg/kg, i.p), but not by the 5-HT(4) receptor antagonist GR 113808 (20 microg/rat, i.c.v.) and the 5-HT(7) receptor antagonist DR 4004 (10 microg/rat, i.c.v.). These data suggest that the inhibitory effect of fluvoxamine on LTP induction is mediated via 5-HT(1A) receptors.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 12480170     DOI： 10.1016/s0006-8993(02)03756-3

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  21 in total

1.  Chronic treatment with milnacipran reverses the impairment of synaptic plasticity induced by conditioned fear stress.

Authors:  Machiko Matsumoto; Kaori Tachibana; Hiroko Togashi; Kazue Tahara; Taku Kojima; Taku Yamaguchi; Mitsuhiro Yoshioka
Journal:  Psychopharmacology (Berl)       Date:  2004-12-24       Impact factor: 4.530

2.  Effects of venlafaxine and escitalopram treatments on NMDA receptors in the rat depression model.

Authors:  Nigar Yilmaz; Arif Demirdas; Mustafa Yilmaz; Recep Sutcu; Aynur Kirbas; Medine Cumhur Cure; Ibrahim Eren
Journal:  J Membr Biol       Date:  2011-07-14       Impact factor: 1.843

Review 3.  Towards a glutamate hypothesis of depression: an emerging frontier of neuropsychopharmacology for mood disorders.

Authors:  Gerard Sanacora; Giulia Treccani; Maurizio Popoli
Journal:  Neuropharmacology       Date:  2011-08-03       Impact factor: 5.250

4.  Differential roles of the dopamine 1-class receptors, D1R and D5R, in hippocampal dependent memory.

Authors:  Joshua Sariñana; Takashi Kitamura; Patrik Künzler; Lisa Sultzman; Susumu Tonegawa
Journal:  Proc Natl Acad Sci U S A       Date:  2014-05-19       Impact factor: 11.205

Review 5.  5-HT1A receptor-regulated signal transduction pathways in brain.

Authors:  Abigail M Polter; Xiaohua Li
Journal:  Cell Signal       Date:  2010-04-02       Impact factor: 4.315

6.  Dopamine transporter blockade increases LTP in the CA1 region of the rat hippocampus via activation of the D3 dopamine receptor.

Authors:  Jarod Swant; John J Wagner
Journal:  Learn Mem       Date:  2006 Mar-Apr       Impact factor: 2.460

Review 7.  About sleep's role in memory.

Authors:  Björn Rasch; Jan Born
Journal:  Physiol Rev       Date:  2013-04       Impact factor: 37.312

8.  The effects of chronic ethanol self-administration on hippocampal 5-HT1A receptors in monkeys.

Authors:  Elizabeth J Burnett; Kathleen A Grant; April T Davenport; Scott E Hemby; David P Friedman
Journal:  Drug Alcohol Depend       Date:  2014-01-15       Impact factor: 4.492

9.  Methamphetamine reduces LTP and increases baseline synaptic transmission in the CA1 region of mouse hippocampus.

Authors:  Jarod Swant; Sanika Chirwa; Gregg Stanwood; Habibeh Khoshbouei
Journal:  PLoS One       Date:  2010-06-30       Impact factor: 3.240

10.  Chronic Enhancement of Serotonin Facilitates Excitatory Transcranial Direct Current Stimulation-Induced Neuroplasticity.

Authors:  Hsiao-I Kuo; Walter Paulus; Giorgi Batsikadze; Asif Jamil; Min-Fang Kuo; Michael A Nitsche
Journal:  Neuropsychopharmacology       Date:  2015-09-02       Impact factor: 7.853
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.