Literature DB >> 12479616

The state of the union: the cell biology of fertilization.

Janice P Evans1, Harvey M Florman.   

Abstract

Fertilization is the process by which sperm and egg unite. An expanded understanding of the mechanisms that underlie these events has provided insights into an important aspect of early development and also has proven to be a valuable model in which to study cellular function. In addition, many emerging strategies for contraception and for the treatment of infertility are based on the mechanism of gamete interaction. Here, we discuss the cell and molecular biology of mammalian fertilization, highlight selected recent breakthroughs and attempt to identify key unanswered questions.

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Mesh:

Year:  2002        PMID: 12479616     DOI: 10.1038/ncb-nm-fertilityS57

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN: 1465-7392            Impact factor:   28.824


  25 in total

1.  Membrane depolarization increases membrane PtdIns(4,5)P2 levels through mechanisms involving PKC βII and PI4 kinase.

Authors:  Xingjuan Chen; Xuan Zhang; Caixia Jia; Jiaxi Xu; Haixia Gao; Guohong Zhang; Xiaona Du; Hailin Zhang
Journal:  J Biol Chem       Date:  2011-09-27       Impact factor: 5.157

Review 2.  Vertebrate Reproduction.

Authors:  Sally Kornbluth; Rafael Fissore
Journal:  Cold Spring Harb Perspect Biol       Date:  2015-10-01       Impact factor: 10.005

Review 3.  Synthetic cannabinoids and potential reproductive consequences.

Authors:  Xiaofei Sun; Sudhansu K Dey
Journal:  Life Sci       Date:  2013-07-01       Impact factor: 5.037

4.  microRNA profiling in three main stages during porcine spermatogenesis.

Authors:  Zonggang Luo; Yingkai Liu; Lei Chen; Michael Ellis; Mingzhou Li; Jinyong Wang; Yi Zhang; Penghui Fu; Ketian Wang; Xuewei Li; Ling Wang
Journal:  J Assist Reprod Genet       Date:  2015-01-07       Impact factor: 3.412

5.  Excision of Trpv6 gene leads to severe defects in epididymal Ca2+ absorption and male fertility much like single D541A pore mutation.

Authors:  Petra Weissgerber; Ulrich Kriebs; Volodymyr Tsvilovskyy; Jenny Olausson; Oliver Kretz; Christof Stoerger; Stefanie Mannebach; Ulrich Wissenbach; Rudi Vennekens; Ralf Middendorff; Veit Flockerzi; Marc Freichel
Journal:  J Biol Chem       Date:  2012-03-15       Impact factor: 5.157

6.  Sphingosine 1-phosphate and sphingosine kinase are involved in a novel signaling pathway leading to acrosomal exocytosis.

Authors:  Laila Suhaiman; Gerardo A De Blas; Lina M Obeid; Alberto Darszon; Luis S Mayorga; Silvia A Belmonte
Journal:  J Biol Chem       Date:  2010-03-17       Impact factor: 5.157

Review 7.  Aspects of endocannabinoid signaling in periimplantation biology.

Authors:  Xiaofei Sun; Sudhansu K Dey
Journal:  Mol Cell Endocrinol       Date:  2008-01-18       Impact factor: 4.102

Review 8.  Endocannabinoid signaling in female reproduction.

Authors:  Xiaofei Sun; Sudhansu K Dey
Journal:  ACS Chem Neurosci       Date:  2012-03-03       Impact factor: 4.418

9.  Targeted disruption of tyrosylprotein sulfotransferase-2, an enzyme that catalyzes post-translational protein tyrosine O-sulfation, causes male infertility.

Authors:  Atefeh Borghei; Ying-Bin Ouyang; Andrew D Westmuckett; Matthew R Marcello; Carlisle P Landel; Janice P Evans; Kevin L Moore
Journal:  J Biol Chem       Date:  2006-02-09       Impact factor: 5.157

10.  Evidence that phosphatidylinositol 3-kinase is involved in sperm-induced tyrosine kinase signaling in Xenopus egg fertilization.

Authors:  Gunay Mammadova; Tetsushi Iwasaki; Alexander A Tokmakov; Yasuo Fukami; Ken-ichi Sato
Journal:  BMC Dev Biol       Date:  2009-12-17       Impact factor: 1.978

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