Literature DB >> 12479609

Are we ignoring potential dangers of in vitro fertilization and related treatments?

Robert M L Winston1, Kate Hardy.   

Abstract

By conventional assessments, in vitro fertilization (IVF) is one of the safest medical treatments. But producing new life brings immense responsibilities. Recently, there have been disquieting reports of foetal abnormality after these treatments and here we evaluate the potential risks associated with intracytoplasmic sperm injection (ICSI), embryo freezing and pre-implantation genetic diagnosis. In our opinion, before translating new techniques into practice, more research, particularly in animals,is desirable. In addition, better child follow-up and a fresh approach to regulation are also needed.

Entities:  

Keywords:  Empirical Approach; Genetics and Reproduction

Mesh:

Year:  2002        PMID: 12479609     DOI: 10.1038/ncb-nm-fertilityS14

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN: 1465-7392            Impact factor:   28.824


  10 in total

Review 1.  Assisted conception. II--in vitro fertilisation and intracytoplasmic sperm injection.

Authors:  Peter Braude; Paula Rowell
Journal:  BMJ       Date:  2003-10-11

Review 2.  Treatment of infertility in men with spinal cord injury.

Authors:  Nancy L Brackett; Charles M Lynne; Emad Ibrahim; Dana A Ohl; Jens Sønksen
Journal:  Nat Rev Urol       Date:  2010-02-16       Impact factor: 14.432

Review 3.  Blastocyst environment and its influence on offspring cardiovascular health: the heart of the matter.

Authors:  Adam J Watkins; Tom P Fleming
Journal:  J Anat       Date:  2009-02-09       Impact factor: 2.610

4.  Evaluation of blastomere biopsy using a mouse model indicates the potential high risk of neurodegenerative disorders in the offspring.

Authors:  Yang Yu; Jindao Wu; Yong Fan; Zhuo Lv; Xuejiang Guo; Chun Zhao; Rong Zhou; Zhuo Zhang; Fuqiang Wang; Min Xiao; Ling Chen; Hui Zhu; Wen Chen; Min Lin; Jiayin Liu; Zuomin Zhou; Liu Wang; Ran Huo; Qi Zhou; Jiahao Sha
Journal:  Mol Cell Proteomics       Date:  2009-03-11       Impact factor: 5.911

5.  Blastomere biopsy influences epigenetic reprogramming during early embryo development, which impacts neural development and function in resulting mice.

Authors:  Yibo Wu; Zhuo Lv; Yang Yang; Guoying Dong; Yang Yu; Yiqiang Cui; Man Tong; Liu Wang; Zuomin Zhou; Hui Zhu; Qi Zhou; Jiahao Sha
Journal:  Cell Mol Life Sci       Date:  2013-09-14       Impact factor: 9.261

6.  Neonatal outcomes among multiple births ≤ 32 weeks gestational age: does mode of conception have an impact? A cohort study.

Authors:  Vibhuti Shah; Haydi Alwassia; Karan Shah; Woojin Yoon; Prakeshkumar Shah
Journal:  BMC Pediatr       Date:  2011-06-14       Impact factor: 2.125

7.  In vitro matured oocytes are more susceptible than in vivo matured oocytes to mock ICSI induced functional and genetic changes.

Authors:  Shubhashree Uppangala; Shilly Dhiman; Sujit Raj Salian; Vikram Jeet Singh; Guruprasad Kalthur; Satish Kumar Adiga
Journal:  PLoS One       Date:  2015-03-18       Impact factor: 3.240

Review 8.  Ooplasmic transfer in human oocytes: efficacy and concerns in assisted reproduction.

Authors:  Sara Darbandi; Mahsa Darbandi; Hamid Reza Khorram Khorshid; Mohammad Reza Sadeghi; Ashok Agarwal; Pallav Sengupta; Safaa Al-Hasani; Mohammad Mehdi Akhondi
Journal:  Reprod Biol Endocrinol       Date:  2017-10-02       Impact factor: 5.211

Review 9.  Infertility in men with spinal cord injury: research and treatment.

Authors:  Nancy L Brackett
Journal:  Scientifica (Cairo)       Date:  2012-11-25

10.  Integrated multi-omics reveal epigenomic disturbance of assisted reproductive technologies in human offspring.

Authors:  Wei Chen; Yong Peng; Xinyi Ma; Siming Kong; Shuangyan Tan; Yuan Wei; Yangyu Zhao; Wenxin Zhang; Yang Wang; Liying Yan; Jie Qiao
Journal:  EBioMedicine       Date:  2020-10-21       Impact factor: 8.143

  10 in total

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