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Literature DB >> 1247887

Effects of antisera to S-100 protein and to synaptic membrane fraction on maze performance and EEG.

Abstract

Topical cortical injection into rats of antiserum to the synaptic membrane fraction caused recurrent spiking activity as observed in the EEG; neither antiserum to S-100 protein nor antiserum to myelin caused any such abnormality. These same rats, when observed on a maze learning task (Lashley III) responded differently to the different antisera. Rats receiving injections of antiserum to the synaptic membrane fraction or antiserum to S-100 protein were inhibited in their performance, while rats injected with antiserum to myelin behaved like uninjected animals.

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Year: 1976 PMID： 1247887 DOI： 10.1016/0006-8993(76)90885-4

Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252

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Cited

9 in total

9. Changes in S-100 protein serum levels in survivors of out-of-hospital cardiac arrest treated with mild therapeutic hypothermia: a prospective, observational study.

Authors: Matthias Derwall; Christian Stoppe; David Brücken; Rolf Rossaint; Michael Fries
Journal: Crit Care Date: 2009-04-16 Impact factor: 9.097

9 in total

Effects of antisera to S-100 protein and to synaptic membrane fraction on maze performance and EEG.

Review 1. [Neuromonitoring with S-100 protein in the intensive care unit].

2. Functional role of the neurospecific S-100 protein in the processes of memory.

3. Nervous system-specific proteins of vertebrates : A search for functions and physiologicla roles.

4. Antiserum against S-100 protein prevents long term potentiation through a cAMP-related mechanism.

5. Influence of immunization with neurospecific proteins and tubulin on learning in rats.

6. S100, a brain-specific protein: localization and possible role in the snail nervous system.

7. The involvement of neurotrophic factors in the central mechanisms of behavior in adult animals.

Review 8. Controversies in lupus: nervous system involvement.

9. Changes in S-100 protein serum levels in survivors of out-of-hospital cardiac arrest treated with mild therapeutic hypothermia: a prospective, observational study.