Literature DB >> 12477453

Vulvar carcinoma presenting during pregnancy, associated with recurrent bone marrow hypoplasia: a case report and literature review.

Shagaf H Bakour1, Henna Jaleel, Judith B Weaver, Sean Kehoe, Keith W Radcliffe.   

Abstract

BACKGROUND: Carcinoma of the vulva has predominantly been a disease of the elderly. Although occasionally it occurs in women under the age of 40 years, carcinoma of the vulva has been rarely diagnosed in pregnancy. Bone marrow hypoplasia can occur as a transient, pregnancy-related event; however, the recurrence of this pathology in future pregnancies is quite rare in the literature. CASE: A 29-year-old woman in her second pregnancy that was complicated by bone marrow hypoplasia had developed a squamous vulvar carcinoma. Each of these two conditions are quite rare in pregnancy, they may have occurred by chance, but there is a hypothetical possibility that bone marrow hypoplasia is an autoimmune disorder, with vulvar carcinoma occurring as a further complication in this immunoimpaired individual.
CONCLUSION: This case also emphasizes the need to consider malignancy as a differential diagnosis in vulvar ulcers occurring in young women.

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Mesh:

Year:  2002        PMID: 12477453     DOI: 10.1006/gyno.2002.6802

Source DB:  PubMed          Journal:  Gynecol Oncol        ISSN: 0090-8258            Impact factor:   5.482


  2 in total

1.  Vulvar carcinoma in pregnant women aged less than 40 years: case report.

Authors:  Malihe Hasanzadeh; Amir Zamiri-Akhlaghi; Maryam Hassanpoor-Moghaddam; Soodabeh Shahidsales
Journal:  Iran J Cancer Prev       Date:  2014

Review 2.  Gynecologic malignancy in pregnancy.

Authors:  Yong Il Ji; Ki Tae Kim
Journal:  Obstet Gynecol Sci       Date:  2013-09-14
  2 in total

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