| Literature DB >> 12477409 |
Christoph Berndt1, Dawadschargal Bech-Otschir, Wolfgang Dubiel, Michael Seeger.
Abstract
The isopeptide bonds formed by ubiquitin or its relatives are cleaved by hydrolases with active site cysteines. Recent studies have revealed that similar metalloprotease motifs--JAMMs--in the Rpn11 subunit of the 26S proteasome lid and in the Csn5 subunit of the COP9 signalosome are involved in deubiquitination and deneddylation, respectively.Entities:
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Year: 2002 PMID： 12477409 DOI： 10.1016/s0960-9822(02)01317-9
Source DB: PubMed Journal: Curr Biol ISSN： 0960-9822 Impact factor: 10.834