Literature DB >> 12475945

Characterization of human alpha-dystrobrevin isoforms in HL-60 human promyelocytic leukemia cells undergoing granulocytic differentiation.

Agné Kulyte1, Ruta Navakauskiene, Grazina Treigyte, Arunas Gineitis, Tomas Bergman, Karl-Eric Magnusson.   

Abstract

The biochemical properties and spatial localization of the protein alpha-dystrobrevin and other isoforms were investigated in cells of the human promyelocytic leukemia line HL-60 granulocytic differentiation as induced by retinoic acid (RA). Alpha-dystrobrevin was detected both in the cytosol and the nuclei of these cells, and a short isoform (gamma-dystrobrevin) was modified by tyrosine phosphorylation soon after the onset of the RA-triggered differentiation. Varying patterns of distribution of alpha-dystrobrevin and its isoforms could be discerned in HL-60 promyelocytes, RA-differentiated mature granulocytes, and human neutrophils. Moreover, the gamma-dystrobrevin isoform was found in association with actin and myosin light chain. The results provide new information about potential involvement of alpha-dystrobrevin and its splice isoforms in signal transduction in myeloid cells during induction of granulocytic differentiation and/or at the commitment stage of differentiation or phagocytic cells.

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Year:  2002        PMID： 12475945      PMCID： PMC138626          DOI： 10.1091/mbc.e02-03-0128

Source DB:  PubMed          Journal:  Mol Biol Cell        ISSN： 1059-1524            Impact factor:   4.138


  44 in total

1.  Dystrobrevin- and dystrophin-like mutants display similar phenotypes in the nematode Caenorhabditis elegans.

Authors:  K Gieseler; C Bessou; L Ségalat
Journal:  Neurogenetics       Date:  1999-04       Impact factor: 2.660

2.  Biochemical evidence for association of dystrobrevin with the sarcoglycan-sarcospan complex as a basis for understanding sarcoglycanopathy.

Authors:  M Yoshida; H Hama; M Ishikawa-Sakurai; M Imamura; Y Mizuno; K Araishi; E Wakabayashi-Takai; S Noguchi; T Sasaoka; E Ozawa
Journal:  Hum Mol Genet       Date:  2000-04-12       Impact factor: 6.150

Review 3.  Function of the cytoskeleton in human neutrophils and methods for evaluation.

Authors:  M Torres; T D Coates
Journal:  J Immunol Methods       Date:  1999-12-17       Impact factor: 2.303

4.  Alternative splicing regulates the nuclear or cytoplasmic localization of dystrophin Dp71.

Authors:  E González; C Montañez; P N Ray; P L Howard; F García-Sierra; D Mornet; B Cisneros
Journal:  FEBS Lett       Date:  2000-10-06       Impact factor: 4.124

Review 5.  Endogenous nitric oxide synthesis: biological functions and pathophysiology.

Authors:  D S Bredt
Journal:  Free Radic Res       Date:  1999-12

6.  The actin-driven movement and formation of acetylcholine receptor clusters.

Authors:  Z Dai; X Luo; H Xie; H B Peng
Journal:  J Cell Biol       Date:  2000-09-18       Impact factor: 10.539

7.  The genomic organization of human dystrobrevin.

Authors:  H M Sadoulet-Puccio; C A Feener; D J Schaid; S N Thibodeau; V V Michels; L M Kunkel
Journal:  Neurogenetics       Date:  1997-05       Impact factor: 2.660

Review 8.  Formation of the neuromuscular junction. Agrin and its unusual receptors.

Authors:  W Hoch
Journal:  Eur J Biochem       Date:  1999-10-01

9.  Maturation and maintenance of the neuromuscular synapse: genetic evidence for roles of the dystrophin--glycoprotein complex.

Authors:  R M Grady; H Zhou; J M Cunningham; M D Henry; K P Campbell; J R Sanes
Journal:  Neuron       Date:  2000-02       Impact factor: 17.173

10.  Different dystrophin-like complexes are expressed in neurons and glia.

Authors:  D J Blake; R Hawkes; M A Benson; P W Beesley
Journal:  J Cell Biol       Date:  1999-11-01       Impact factor: 10.539
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  7 in total

1.  α-Dystrobrevin distribution and association with other proteins in human promyelocytic NB4 cells treated for granulocytic differentiation.

Authors:  V V Borutinskaite; K-E Magnusson; R Navakauskiene
Journal:  Mol Biol Rep       Date:  2010-01-29       Impact factor: 2.316

2.  Association of alpha-dystrobrevin with reorganizing tight junctions.

Authors:  A Sjö; K E Magnusson; K H Peterson
Journal:  J Membr Biol       Date:  2005-01       Impact factor: 1.843

3.  Platelet adhesion: structural and functional diversity of short dystrophin and utrophins in the formation of dystrophin-associated-protein complexes related to actin dynamics.

Authors:  Doris Cerecedo; Dalila Martínez-Rojas; Oscar Chávez; Francisco Martínez-Pérez; Francisco García-Sierra; Alvaro Rendon; Dominique Mornet; Ricardo Mondragón
Journal:  Thromb Haemost       Date:  2005-12       Impact factor: 5.249

Review 4.  Dystrophin Dp71: the smallest but multifunctional product of the Duchenne muscular dystrophy gene.

Authors:  Ramin Tadayoni; Alvaro Rendon; L E Soria-Jasso; Bulmaro Cisneros
Journal:  Mol Neurobiol       Date:  2011-11-22       Impact factor: 5.590

5.  Histone deacetylase inhibitor BML-210 induces growth inhibition and apoptosis and regulates HDAC and DAPC complex expression levels in cervical cancer cells.

Authors:  Veronika V Borutinskaite; Karl-Eric Magnusson; Ruta Navakauskiene
Journal:  Mol Biol Rep       Date:  2012-09-26       Impact factor: 2.316

6.  An RNAi Screening of Clinically Relevant Transcription Factors Regulating Human Adipogenesis and Adipocyte Metabolism.

Authors:  Christel Björk; Narmadha Subramanian; Jianping Liu; Juan Ramon Acosta; Beatriz Tavira; Anders B Eriksson; Peter Arner; Jurga Laurencikiene
Journal:  Endocrinology       Date:  2021-07-01       Impact factor: 4.736

7.  MicroRNAs regulate human adipocyte lipolysis: effects of miR-145 are linked to TNF-α.

Authors:  Silvia Lorente-Cebrián; Niklas Mejhert; Agné Kulyté; Jurga Laurencikiene; Gaby Åström; Pér Hedén; Mikael Rydén; Peter Arner
Journal:  PLoS One       Date:  2014-01-24       Impact factor: 3.240
  7 in total

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