Literature DB >> 12475309

A remarkably efficient synthesis of pure cis-stilbenoid hydrocarbons using trans-dibromoalkenes via palladium catalysis.

Rajendra Rathore1, Mihaela I Deselnicu, Carrie L Burns.   

Abstract

A remarkably versatile synthesis of cis-stilbenoid hydrocarbons containing highly functionalized phenyl groups is developed via an efficient palladium-catalyzed coupling of aryl Grignard reagents with trans-1,2-dibromoalkenes (generally obtained via bromination of the corresponding dialkylacetylenes) in tetrahydrofuran.

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Year:  2002        PMID: 12475309     DOI: 10.1021/ja027421w

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  1 in total

1.  Two palladium-catalyzed domino reactions from one set of substrates/reagents: efficient synthesis of substituted indenes and cis-stilbenoid hydrocarbons from the same internal alkynes and hindered Grignard reagents.

Authors:  Cheng-Guo Dong; Pik Yeung; Qiao-Sheng Hu
Journal:  Org Lett       Date:  2007-01-18       Impact factor: 6.005

  1 in total

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