Literature DB >> 12474485

Onchocerciasis-associated morbidity: hypothesis.

Anthony R Mawson1, Musau WaKabongo.   

Abstract

Tissue concentrations of vitamin A in Onchocerca volvulus are about 8 times higher than those of the host. About 100,000 microfilariae (mf) die every day in heavily infected persons. Onchocerciasis-associated morbidity may be due in part to the release of retinoids from dying mf and their gradual accumulation to toxic concentrations in affected tissues.

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Year:  2002        PMID: 12474485     DOI: 10.1016/s0035-9203(02)90434-7

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN: 0035-9203            Impact factor:   2.184


  4 in total

1.  Nematode parasites reduce carotenoid-based signalling in male red grouse.

Authors:  Jesús Martínez-Padilla; François Mougeot; Lorenzo Pérez-Rodríguez; Gary R Bortolotti
Journal:  Biol Lett       Date:  2007-04-22       Impact factor: 3.703

2.  Retinoid Expression in Onchocercal Skin Disease: Pilot Study.

Authors:  Anthony R Mawson; Williams H Makunde; Alan D Penman; Veronica de Los Angeles Hernandez Morales; Akili K Kalinga; Filbert Francis; Semyon Rubinchik; Addow Kibweja
Journal:  Infect Dis (Auckl)       Date:  2017-09-20

3.  Identification and characterization of the Onchocerca volvulus Excretory Secretory Product Ov28CRP, a putative GM2 activator protein.

Authors:  Ferdinand Ngale Njume; Stephen Mbigha Ghogomu; Robert Adamu Shey; Lea Olive Tchouate Gainkam; Philippe Poelvoorde; Perrine Humblet; Joseph Kamgno; Annie Robert; Leon Mutesa; Christophe Lelubre; Evelina Edelweiss; Arnaud Poterszman; Susi Anheuser; Luc Vanhamme; Jacob Souopgui
Journal:  PLoS Negl Trop Dis       Date:  2019-07-22

Review 4.  Advances in Antiwolbachial Drug Discovery for Treatment of Parasitic Filarial Worm Infections.

Authors:  Malina A Bakowski; Case W McNamara
Journal:  Trop Med Infect Dis       Date:  2019-07-18
  4 in total

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