Literature DB >> 12472677

Neutralization titres and vertical HIV-1 transmission.

V Bongertz1, C I Costa, V G Veloso, B Grinsztejn, E C J Filho, G Calvet, J H Pilotto.   

Abstract

Replication of the human immunodeficiency virus type 1 (HIV-1) isolate MN in CEM cells was less neutralized by the plasma from the mothers of infected children (MIC) in comparison with the plasma from the mothers of uninfected children (MUC). Significantly higher neutralization titres were observed for the sera from MUCs compared with MICs, and only the sera from MUC showed 100% neutralization of the HIV-1 MN strain. We suggest that a simple neutralization assay as described here could be useful in prognostic analyses.

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Year:  2002        PMID： 12472677     DOI： 10.1046/j.1365-3083.2002.01174.x

Source DB:  PubMed          Journal:  Scand J Immunol        ISSN： 0300-9475            Impact factor:   3.487


  7 in total

1.  Neutralization escape variants of human immunodeficiency virus type 1 are transmitted from mother to infant.

Authors:  Xueling Wu; Adam B Parast; Barbra A Richardson; Ruth Nduati; Grace John-Stewart; Dorothy Mbori-Ngacha; Stephanie M J Rainwater; Julie Overbaugh
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

2.  The breadth and potency of passively acquired human immunodeficiency virus type 1-specific neutralizing antibodies do not correlate with the risk of infant infection.

Authors:  John B Lynch; Ruth Nduati; Catherine A Blish; Barbra A Richardson; Jennifer M Mabuka; Zahra Jalalian-Lechak; Grace John-Stewart; Julie Overbaugh
Journal:  J Virol       Date:  2011-03-16       Impact factor: 5.103

3.  Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.

Authors:  Amit Kumar; Claire E P Smith; Elena E Giorgi; Joshua Eudailey; David R Martinez; Karina Yusim; Ayooluwa O Douglas; Lisa Stamper; Erin McGuire; Celia C LaBranche; David C Montefiori; Genevieve G Fouda; Feng Gao; Sallie R Permar
Journal:  PLoS Pathog       Date:  2018-04-19       Impact factor: 6.823

4.  Induction of Neutralizing Responses against Autologous Virus in Maternal HIV Vaccine Trials.

Authors:  Eliza D Hompe; Jesse F Mangold; Amit Kumar; Joshua A Eudailey; Erin McGuire; Barton F Haynes; M Anthony Moody; Peter F Wright; Genevieve G Fouda; Elena E Giorgi; Feng Gao; Sallie R Permar
Journal:  mSphere       Date:  2020-06-03       Impact factor: 4.389

5.  Mutations that confer resistance to broadly-neutralizing antibodies define HIV-1 variants of transmitting mothers from that of non-transmitting mothers.

Authors:  Amit Kumar; Elena E Giorgi; Joshua J Tu; David R Martinez; Joshua Eudailey; Michael Mengual; Manukumar Honnayakanahalli Marichannegowda; Russell Van Dyke; Feng Gao; Sallie R Permar
Journal:  PLoS Pathog       Date:  2021-04-02       Impact factor: 7.464

Review 6.  The role of neutralizing antibodies in prevention of HIV-1 infection: what can we learn from the mother-to-child transmission context?

Authors:  Martine Braibant; Francis Barin
Journal:  Retrovirology       Date:  2013-10-07       Impact factor: 4.602

7.  Maternal Neutralization-Resistant Virus Variants Do Not Predict Infant HIV Infection Risk.

Authors:  Caitlin Milligan; Maxwel M Omenda; Vrasha Chohan; Katherine Odem-Davis; Barbra A Richardson; Ruth Nduati; Julie Overbaugh
Journal:  mBio       Date:  2016-02-02       Impact factor: 7.867
  7 in total

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