Literature DB >> 12470902

DNA methylation in cancer and ageing.

Yasuhito Yuasa1.   

Abstract

Epigenetic gene silencing through DNA methylation is now clearly thought to be one of the important steps in the mechanism underlying tumourigenesis. The methylation of several genes increases with age in normal tissues such as the colon. Methylation related to cancer and ageing may lead to new biomarkers and therapeutic concepts for cancer. Copyright 2002 Published by Elsevier Science Ireland Ltd.

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Year:  2002        PMID： 12470902     DOI： 10.1016/s0047-6374(02)00100-8

Source DB:  PubMed          Journal:  Mech Ageing Dev        ISSN： 0047-6374            Impact factor:   5.432


  5 in total

Review 1.  Colorectal cancer: a model for epigenetic tumorigenesis.

Authors:  J J L Wong; N J Hawkins; R L Ward
Journal:  Gut       Date:  2006-07-13       Impact factor: 23.059

2.  Telomere position effect and silencing of transgenes near telomeres in the mouse.

Authors:  Mehrdad Pedram; Carl N Sprung; Qing Gao; Anthony W I Lo; Gloria E Reynolds; John P Murnane
Journal:  Mol Cell Biol       Date:  2006-03       Impact factor: 4.272

3.  Decline in genomic DNA methylation through aging in a cohort of elderly subjects.

Authors:  Valentina Bollati; Joel Schwartz; Robert Wright; Augusto Litonjua; Letizia Tarantini; Helen Suh; David Sparrow; Pantel Vokonas; Andrea Baccarelli
Journal:  Mech Ageing Dev       Date:  2008-12-27       Impact factor: 5.432

4.  Correlation between promoter methylation of p14(ARF), TMS1/ASC, and DAPK, and p53 mutation with prognosis in cholangiocarcinoma.

Authors:  Liu Xiaofang; Tang Kun; Yu Shaoping; Wang Zaiqiu; Su Hailong
Journal:  World J Surg Oncol       Date:  2012-01-09       Impact factor: 2.754

5.  Breast cancer risk and imprinting methylation in blood.

Authors:  Kristina Harrison; Gwen Hoad; Paula Scott; Louise Simpson; Graham W Horgan; Elizabeth Smyth; Steven D Heys; Paul Haggarty
Journal:  Clin Epigenetics       Date:  2015-09-04       Impact factor: 6.551
  5 in total

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