Literature DB >> 12470764

Benign intracranial hypertension and thyreostimulin suppression hormonotherapy.

Jacques Serratrice1, Brigitte Granel, John Conrath, Henri Dufour, Patrick Disdier, Jean François Henry, Pierre-Jean Weiller.   

Abstract

PURPOSE: To report a case of benign intracranial hypertension occurring during thyreostimulin suppression hormonotherapy after thyroidectomy for papillary cancer.
DESIGN: Interventional case report.
METHODS: A 45-year-old woman underwent total thyroidectomy for a 7-mm papillary cancer. Seventeen years later, she experienced headache, dizziness, irritability, sensation of full head, and blurred vision of the right eye while being treated with a mix of L thyroxin (LT4) and liothyronin (LT3). Ophthalmological data (including the presence of papilledema), cerebroorbital magnetic resonance imaging, and lumbar pressure evaluation confirmed benign intracranial hypertension.
RESULTS: Substitutive hormonotherapy was decreased under specialized surveillance, permitting remission of benign intracranial hypertension symptoms and papilledema.
CONCLUSIONS: Benign intracranial hypertension is usually difficult to cure, and its association with thyroid hormonotherapy is rare. In our patient, tapering LT4 and withdrawal of LT3 until a euthyroidal state was obtained resulted in successful treatment of benign intracranial hypertension.

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Year:  2002        PMID: 12470764     DOI: 10.1016/s0002-9394(02)01852-4

Source DB:  PubMed          Journal:  Am J Ophthalmol        ISSN: 0002-9394            Impact factor:   5.258


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