Literature DB >> 12470398

Coronary artery bypass grafting combined with aortic valve replacement in healthy octogenarians does not increase postoperative risk.

Harald Brunvand1, Jon Offstad, Sigurd Nitter-Hauge, Jan Ludvig Svennevig.   

Abstract

OBJECTIVE: Critical aortic stenosis with or without coronary artery disease is increasingly common in octogenarians. Surgery is the treatment of choice, but indications and results of aortic valve replacement (AVR), particularly when combined with coronary artery bypass grafting (CABG) are debated. We investigated whether the combined procedure of AVR and CABG increased postoperative risk compared with isolated AVR in otherwise healthy octogenarians.
DESIGN: In the period 1994-1998, AVR was performed in 94 patients above 80 years, the majority in NYHA class III and IV. Combined AVR and CABG was performed in 52/94 patients. The patients were studied retrospectively by collecting data from hospital records and followed for 0-7 years.
RESULTS: Mean age was 82 +/- 2.3 years, sex (male/female) 33/61, left ventricular ejection fraction 70 +/- 18%, transvalvular peak pressure gradient 63 +/- 20 mmHg and aortic valve area 0.5 +/- 0.2 cm(2). Early mortality (< 30 days) was 4/42 (9.5%) after AVR and 4/52 (7.6%) after AVR and CABG (p = NS between groups). Three-year survival was 33/42 (78.5%) after AVR and 42/52 (80.7%) after AVR and CABG (p = NS between groups).
CONCLUSION: AVR with concomitant CABG in octogenarians with aortic stenosis who are otherwise healthy, may be performed without increased risk.

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Year:  2002        PMID: 12470398     DOI: 10.1080/140174302320774519

Source DB:  PubMed          Journal:  Scand Cardiovasc J        ISSN: 1401-7431            Impact factor:   1.589


  5 in total

1.  Adding coronary artery bypass grafting to aortic valve replacement increases operative mortality for elderly (70 years and older) patients with aortic stenosis.

Authors:  Yasuyuki Sasaki; Hidekazu Hirai; Mitsuharu Hosono; Yasuyuki Bito; Atsushi Nakahira; Yasuo Suehiro; Daisuke Kaku; Yuko Okada; Shigefumi Suehiro
Journal:  Gen Thorac Cardiovasc Surg       Date:  2013-03-15

2.  Coronary artery bypass grafting added to surgical aortic valve replacement in octogenarians.

Authors:  Luigi Spadafora; Marco Bernardi; Giuseppe Biondi-Zoccai; Giacomo Frati
Journal:  Interact Cardiovasc Thorac Surg       Date:  2022-07-09

3.  The early and long-term outcomes of coronary artery bypass grafting added to aortic valve replacement compared to isolated aortic valve replacement in elderly patients: a systematic review and meta-analysis.

Authors:  Stefano D'Alessandro; Domenico Tuttolomondo; Gurmeet Singh; Daniel Hernandez-Vaquero; Claudia Pattuzzi; Alan Gallingani; Francesco Maestri; Francesco Nicolini; Francesco Formica
Journal:  Heart Vessels       Date:  2022-05-09       Impact factor: 1.814

4.  The impact of coronary artery bypass grafting added to aortic valve replacement on long-term outcomes in octogenarian patients: a reconstructed time-to-event meta-analysis.

Authors:  Alan Gallingani; Stefano D'Alessandro; Gurmeet Singh; Daniel Hernandez-Vaquero; Mevlüt Çelik; Evelina Ceccato; Francesco Nicolini; Francesco Formica
Journal:  Interact Cardiovasc Thorac Surg       Date:  2022-07-09

5.  Aortic valve replacement in octogenarians.

Authors:  Amal K Bose; James D Aitchison; John H Dark
Journal:  J Cardiothorac Surg       Date:  2007-07-13       Impact factor: 1.637

  5 in total

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